Department of Fisheries and Marine Science, Noakhali Science and Technology University, Noakhali, Bangladesh.
Forensic Science Laboratory, Rapid Action Battalions Headquarters, Dhaka, 1229, Bangladesh.
Environ Sci Pollut Res Int. 2018 Nov;25(31):31727-31736. doi: 10.1007/s11356-018-3158-9. Epub 2018 Sep 12.
Metals tend to accumulate in higher organisms, e.g., fish and human through biomagnification effects in food chain. So, their presence in any component of the environment has become a global ecosystem and health concern. Here, we measured four health concerned metals like As, Cr, Mn, and Hg via inductively coupled plasma-mass spectrometry (ICP-MS) and analyzed applying some chemometrics for the assessment of human health risk through consumption of Puntius ticto, a very commonly consumed small fish in Bangladesh. The average concentration (wet weight) of metals was in the following descending order: Hg (0.006 mg/kg) > Cr (0.004 mg/kg) > Mn (0.003 mg/kg) > As (0.002 mg/kg). Hg level exceeded the provisional tolerable weekly intake (PTWI), and all other metals were within the permissible limit. The estimated daily intake (EDI) index of heavy metals showed that all the concentration levels were under the recommended daily intake (RDA) except Hg. Increased level of Hg is of particular concern to human health due to its biomagnification nature and can cause several neurological and physiological disorders including kidney failure. The total target hazard quotients (TTHQs) and carcinogenic risk (CR) matrices revealed that the intakes of Hg and As through fish consumption were higher than the recommended values, indicating consumers' remain non-carcinogenic and carcinogenic (THQ > 1; CR > 10) health risks for lifetime consumption. Multivariate analyses (cluster and principal component) explained the sources of heavy metals in the study area originating from both anthropogenic and geological origin.
金属往往会通过食物链的生物放大效应在高等生物体（如鱼类和人类）中积累。因此，它们在环境中任何成分中的存在都已成为全球生态系统和健康关注的问题。在这里，我们通过电感耦合等离子体质谱（ICP-MS）测量了四种健康相关的金属，如砷（As）、铬（Cr）、锰（Mn）和汞（Hg），并通过应用一些化学计量学方法分析了孟加拉国非常普遍食用的小鱼 Puntus ticto 通过食用这些鱼对人类健康风险的评估。金属的平均浓度（湿重）按以下降序排列：汞（0.006mg/kg）>铬（0.004mg/kg）>锰（0.003mg/kg）>砷（0.002mg/kg）。汞含量超过暂定每周耐受摄入量（PTWI），其他所有金属均在允许范围内。重金属的估计每日摄入量（EDI）指数表明，除汞外，所有浓度水平均低于建议的每日摄入量（RDA）。由于汞的生物放大性质，其水平升高尤其令人关注对人类健康的影响，可能导致多种神经和生理紊乱，包括肾衰竭。总目标危害系数（TTHQ）和致癌风险（CR）矩阵表明，通过鱼类消费摄入的汞和砷含量高于推荐值，这表明消费者在一生中食用时仍然存在非致癌和致癌风险（THQ>1；CR>10）。多元分析（聚类和主成分分析）解释了研究区域重金属的来源，这些重金属来自人为和地质来源。
