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肾癌:下一个十年。

Kidney cancer: The next decade.

机构信息

Francis Crick Institute, London, UK.

The Royal Marsden Hospital, London, UK.

出版信息

J Exp Med. 2018 Oct 1;215(10):2477-2479. doi: 10.1084/jem.20181617. Epub 2018 Sep 14.

DOI:10.1084/jem.20181617
PMID:30217855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6170181/
Abstract

Chris Boshoff, Senior Vice President of Immuno-Oncology, Translational and Early Development at Pfizer, and colleagues Samra Turajlic and Charles Swanton from the Francis Crick Institute and University College London give us their personal point of view on new insights and future therapeutic approaches for renal cancer.

摘要

辉瑞公司免疫肿瘤学、转化和早期研发高级副总裁克里斯·博肖夫(Chris Boshoff)和弗朗西斯·克里克研究所(Francis Crick Institute)及伦敦大学学院的同事萨默拉·图拉利奇(Samra Turajlic)和查尔斯·斯旺顿(Charles Swanton)从个人角度探讨了肾癌的新见解和未来治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/6170181/4b629fa14687/JEM_20181617_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/6170181/4b629fa14687/JEM_20181617_Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4305/6170181/4b629fa14687/JEM_20181617_Fig1.jpg

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Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.阿替利珠单抗单药或联合贝伐珠单抗与舒尼替尼治疗肾细胞癌的临床活性和分子相关性。
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Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.
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