Suppr超能文献

渴望不朽。

Hungering for Immortality.

作者信息

Eissenberg Joel C

机构信息

Joel C. Eissenberg, PhD, is a Professor and Associate Dean for Research, Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine.

出版信息

Mo Med. 2018 Jan-Feb;115(1):12-17.

Abstract

Beyond avoiding risky behavior-smoking, substance abuse, obesity-and embracing healthy habits like exercise, a balanced diet, and non-obese body weight, are there things we each do today to significantly extend our lifespan? Caloric restriction is the only behavioral intervention consistently shown to extend both mean and maximal lifespan across a wide range of species. In most cases, the lifespan extension is accompanied by a marked delay in the onset of age-associated disease and infirmity.

摘要

除了避免吸烟、药物滥用、肥胖等危险行为,并养成运动、均衡饮食和保持非肥胖体重等健康习惯外,我们今天每个人还能做些什么来显著延长寿命呢?热量限制是唯一一种在广泛物种中持续显示能延长平均寿命和最大寿命的行为干预措施。在大多数情况下,寿命延长伴随着与年龄相关疾病和虚弱的发病明显延迟。

相似文献

1
Hungering for Immortality.
Mo Med. 2018 Jan-Feb;115(1):12-17.
2
Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
Aging Cell. 2009 Sep;8(5):607-13. doi: 10.1111/j.1474-9726.2009.00509.x. Epub 2009 Aug 12.
3
Can we live longer by eating less? A review of caloric restriction and longevity.
Maturitas. 2012 Apr;71(4):315-9. doi: 10.1016/j.maturitas.2011.12.017. Epub 2012 Jan 26.
4
Finally, a Regimen to Extend Human Life Expectancy.
Rejuvenation Res. 2018 Jun;21(3):278-282. doi: 10.1089/rej.2018.2088.
5
The Less We Eat, the Longer We Live: Can Caloric Restriction Help Us Become Centenarians?
Int J Mol Sci. 2022 Jun 11;23(12):6546. doi: 10.3390/ijms23126546.
6
Analysis of biomarkers of caloric restriction in aging cells.
Methods Mol Biol. 2013;1048:19-29. doi: 10.1007/978-1-62703-556-9_3.
7
A New Concept in Diet Restriction Is Cleaning Up!
J Gerontol A Biol Sci Med Sci. 2021 Mar 31;76(4):599-600. doi: 10.1093/gerona/glaa195.
8
Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age.
J Gerontol A Biol Sci Med Sci. 2009 Jul;64(7):711-22. doi: 10.1093/gerona/glp051. Epub 2009 May 4.
9
Resveratrol and life extension.
Ann N Y Acad Sci. 2011 Jan;1215:138-43. doi: 10.1111/j.1749-6632.2010.05850.x.
10
Energetic interventions for healthspan and resiliency with aging.
Exp Gerontol. 2016 Dec 15;86:73-83. doi: 10.1016/j.exger.2016.05.012. Epub 2016 May 31.

引用本文的文献

1
Biomarkers of aging: from molecules and surrogates to physiology and function.
Physiol Rev. 2025 Jul 1;105(3):1609-1694. doi: 10.1152/physrev.00045.2024. Epub 2025 Mar 20.
2
Quo Vadis, Dottore? Religious, Philosophical and Medical Perspectives on the Quest for Immortality.
J Relig Health. 2022 Aug;61(4):3177-3191. doi: 10.1007/s10943-022-01591-9. Epub 2022 Jun 11.
3
Could "cellular exercise" be the missing ingredient in a healthy life? Diets, caloric restriction, and exercise-induced hormesis.
Nutrition. 2022 Jul-Aug;99-100:111629. doi: 10.1016/j.nut.2022.111629. Epub 2022 Feb 7.
5
Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.
J Natl Cancer Inst. 2021 Feb 1;113(2):112-122. doi: 10.1093/jnci/djaa060.
6
Beating the Odds on Lifespan.
Mo Med. 2018 Jul-Aug;115(4):337-338.

本文引用的文献

1
Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential.
EBioMedicine. 2017 Jul;21:37-44. doi: 10.1016/j.ebiom.2017.06.015. Epub 2017 Jun 19.
2
From rapalogs to anti-aging formula.
Oncotarget. 2017 May 30;8(22):35492-35507. doi: 10.18632/oncotarget.18033.
3
Dietary protein, aging and nutritional geometry.
Ageing Res Rev. 2017 Oct;39:78-86. doi: 10.1016/j.arr.2017.03.001. Epub 2017 Mar 6.
4
Convergence of Innate and Adaptive Immunity during Human Aging.
Front Immunol. 2016 Nov 4;7:445. doi: 10.3389/fimmu.2016.00445. eCollection 2016.
5
Impact of intermittent fasting on health and disease processes.
Ageing Res Rev. 2017 Oct;39:46-58. doi: 10.1016/j.arr.2016.10.005. Epub 2016 Oct 31.
6
Resveratrol and Lifespan in Model Organisms.
Curr Med Chem. 2016;23(41):4639-4680. doi: 10.2174/0929867323666161024151233.
8
Calorie restriction in humans: An update.
Ageing Res Rev. 2017 Oct;39:36-45. doi: 10.1016/j.arr.2016.08.005. Epub 2016 Aug 17.
9
Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.
Cell Rep. 2016 Jul 12;16(2):520-530. doi: 10.1016/j.celrep.2016.05.092. Epub 2016 Jun 23.
10
Metformin as a Tool to Target Aging.
Cell Metab. 2016 Jun 14;23(6):1060-1065. doi: 10.1016/j.cmet.2016.05.011.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验