Department of Radiology, Mayo Clinic College of Medicine and Science, 200 1st St SW, Rochester, MN 55905, USA.
Department of Radiology, Mayo Clinic College of Medicine and Science, 200 1st St SW, Rochester, MN 55905, USA.
J Mech Behav Biomed Mater. 2019 Jan;89:13-18. doi: 10.1016/j.jmbbm.2018.09.007. Epub 2018 Sep 6.
Pleural effusion manifests as compression of pleural fluid on the lung parenchyma contributing to hypoxemia. Medical procedures such as drainage of plural fluid releases this compression and increases oxygenation. However, the effect of pleural effusion on the elasticity of lung parenchyma is unknown. By using lung ultrasound surface wave elastography (LUSWE) and finite element method (FEM), the effect of pleural effusion on the elasticity of superficial lung parenchyma in terms of surface wave speed measurement was evaluated in a sponge phantom study. Different thicknesses of ultrasound transmission gel used to simulated pleural fluid were inserted into a condom, which was placed between the sponge and standoff pad. A mechanical shaker was used to generate vibration on the sponge phantom at different frequencies ranging from 100 to 300 Hz while the ultrasound transducer was used to capture the motion for measurement of surface wave speed of the sponge. FEM was conducted based on the experimental setup and numerically assessed the influence of pleural effusion on the surface wave speed of the sponge. We found from FEM experiments that the influence of thickness of ultrasound transmission gel was statistically insignificant on the surface wave speed of the sponge at 100 and 150 Hz.
胸腔积液表现为对肺实质的胸腔积液压迫，导致低氧血症。医疗程序，如引流胸腔积液，释放这种压迫并增加氧合。然而，胸腔积液对肺实质弹性的影响尚不清楚。通过使用肺部超声表面波弹性成像（LUSWE）和有限元法（FEM），在海绵体模型研究中评估了胸腔积液对浅层肺实质弹性的影响，通过表面波速度测量来评估。将不同厚度的超声传输凝胶插入避孕套中，将避孕套放置在海绵体和间隔垫之间。机械振动器用于在 100 至 300 Hz 的不同频率下在海绵体模型上产生振动，而超声换能器用于捕获运动以测量海绵体的表面波速度。基于实验设置进行了有限元分析，并数值评估了胸腔积液对海绵体表面波速度的影响。我们从有限元实验中发现，在 100 和 150 Hz 时，超声传输凝胶厚度对海绵体表面波速度的影响在统计学上无显著性意义。
