草药对复发性轻型口腔阿弗他溃疡的影响。

Effect of Herbal on Recurrent Minor Oral Aphthous Ulcer.

作者信息

Khozeimeh Faezeh, Saberi Zahra, Tavangar Atefeh, Badi Fahime Fakhari

机构信息

Dental Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, University Of Medical Sciences, Isfahan, Iran.

Dental Material Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Isfahan University Of Medical Sciences, Isfahan, Iran.

出版信息

Open Dent J. 2018 Aug 31;12:567-571. doi: 10.2174/1874210601812010567. eCollection 2018.

DOI:10.2174/1874210601812010567

PMID:30258501

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6131317/

Abstract

BACKGROUND

The oral aphthous is a common oral ulcer with intense pain and there is no treatment for it, yet. is an herbal medicine that moderated the immune system.

OBJECTIVE

The aim of this study was to investigate the effects of on the treatment of aphthous ulcer.

METHODS

50 patients with minor aphthous participated in our study. 25 patients take 3 tablets in a day for five weeks (case group) and 25 patients didn't take any tablets (control group). The patients were monitored for one month before taking the tablets for six months. During this period, the number of lesions, complete improvement of ulcers, recurrence rate and intensity of pain were considered in each month. Finally, the Friedman and ANOVA tests used to analyze the obtained data.

RESULT

Our study showed a significant difference between a number of lesions during six-month in case and control groups (>0.001). In this way, we observed that the number of lesions was decreased significantly after six months in the case group. Hence, ANOVA analysis showed a significant decrease between each month for the intensity of pain (=0.025), complete improvement (<0.001) and recurrence rate (=0.026).

CONCLUSION

In conclusion, we showed that tablets as an herbal medicine have positive effects on a number of lesions, intensity of pain, complete improvement and recurrence rate in patients with recurrent minor aphthous ulcers.

摘要

背景

复发性口腔溃疡是一种常见的口腔溃疡，疼痛剧烈，目前尚无治疗方法。[某种草药名称]是一种调节免疫系统的草药。

目的

本研究旨在探讨[某种草药名称]对复发性口腔溃疡的治疗效果。

方法

50例轻型复发性口腔溃疡患者参与本研究。25例患者每天服用3片[某种草药名称]，持续5周（病例组），25例患者不服用任何药物（对照组）。在服用药物前对患者进行1个月的监测，之后持续监测6个月。在此期间，每月记录溃疡病变数量、溃疡完全愈合情况、复发率及疼痛强度。最后，采用Friedman检验和方差分析对所得数据进行分析。