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东方甜瓜叶热水提取物促进头发生长并延长生长期毛发周期：及评估。

Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: and evaluation.

作者信息

Pi Long-Quan, Lee Won-Soo, Min Sung Hee

机构信息

Department of Dermatology and Institute of Hair & Cosmetic Medicine, Yonsei University, Wonju College of Medicine, Wonju, Gangwon, 26426 Korea.

1Department of Oriental Medical Food & Nutrition, Semyung University, Jecheon, Chungbuk, 27136 Korea.

出版信息

Food Sci Biotechnol. 2016 Apr 30;25(2):575-580. doi: 10.1007/s10068-016-0080-0. eCollection 2016.

DOI:10.1007/s10068-016-0080-0
PMID:30263308
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6049190/
Abstract

Effects of hot water extracts of oriental melon leaves (OML) on promotion of hair growth were investigated. Topical OML extract administration for hair regeneration was investigated using an model with C57BL/6 mice. Effects of OML extracts on the human hair growth were investigated using a hair follicle organ culture. OML extracts induced a shortened telogen to anagen conversion and promoted hair growth in the C57BL/6 mouse model. Culture of human hair follicles in the presence of OML extracts for 8 days promoted hair growth and prolonged the anagen duration due to induction of hair follicle cell proliferation in the bulb region. OML extracts exert a hair growth promotion effect and, therefore, can be used as a therapeutic agent for prevention of hair loss.

摘要

研究了东方甜瓜叶热水提取物（OML）对促进头发生长的作用。使用C57BL/6小鼠模型研究了局部给予OML提取物促进毛发生长的情况。使用毛囊器官培养研究了OML提取物对人类头发生长的影响。OML提取物在C57BL/6小鼠模型中诱导了休止期到生长期的转换缩短，并促进了头发生长。在OML提取物存在的情况下培养人毛囊8天，可促进头发生长，并由于诱导毛囊球部细胞增殖而延长生长期。OML提取物具有促进头发生长的作用，因此可作为预防脱发的治疗剂。

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Hot water extract of oriental melon leaf promotes hair growth and prolongs anagen hair cycle: and evaluation.东方甜瓜叶热水提取物促进头发生长并延长生长期毛发周期：及评估。
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2
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Mol Biol Rep. 2013 Dec;40(12):6855-62. doi: 10.1007/s11033-013-2803-0. Epub 2013 Oct 5.
3
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4
Effects of calcitonin gene-related peptide on the immune privilege of human hair follicles.降钙素基因相关肽对人毛囊免疫赦免的影响。
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5
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