Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi 39253, Korea.
School of Biomedical Engineering, Korea University, Seoul 02841, Korea.
Sensors (Basel). 2018 Oct 3;18(10):3324. doi: 10.3390/s18103324.
A new multiwavelength visible-range-supported opto⁻ultrasound instrument using a light-emitting diode and ultrasound transducer was developed in order to produce multiwavelength visible light with minimized color aberration errors, and detect ultrasound signals emitted from the target. In the instrument, the developed optical systems can provide multiwavelength optical transmission with low optical aberration within 10-cm ranges that are reasonably flat in the modulation transfer function at spatial frequencies of 20 and 40 lp/mm, except at the end of the diagonal edge of the samples. To assess the instrument capability, we performed pulse⁻echo responses with eye samples. Focused red, green, blue and white light rays from an integrated red, green and blue LED source were produced, and echo signal amplitudes of 33.53, 34.92, 38.74 and 82.54 mV, respectively, were detected from the eye samples by a 10-MHz focused ultrasound transducer. The center frequencies of the echo signal when producing red, green, blue and white LED light in the instrument were 9.02, 9.05, 9.21 and 8.81 MHz, respectively. From these tests, we verify that this instrument can combine red, green and blue LED light to cover different wavelengths in the visible-light range and detect reasonable echo amplitudes from the samples.
为了产生具有最小色差误差的多波长可见光，并检测来自目标的超声信号，开发了一种使用发光二极管和超声换能器的新型多波长可见光谱支持的光电超声仪器。在该仪器中，开发的光学系统可以在调制传递函数的空间频率为 20 和 40 lp/mm 的情况下，在 10cm 范围内提供具有低光学像差的多波长光学传输，除了样品对角线边缘的末端。为了评估仪器的性能，我们使用眼样本进行了脉冲-回波响应。从集成的红、绿、蓝 LED 光源产生聚焦的红、绿、蓝光射线，并通过 10MHz 聚焦超声换能器从眼样本检测到 33.53、34.92、38.74 和 82.54mV 的回波信号幅度。当在仪器中产生红、绿、蓝 LED 光时，回波信号的中心频率分别为 9.02、9.05、9.21 和 8.81MHz。通过这些测试，我们验证了该仪器可以组合红、绿、蓝 LED 光以覆盖可见光范围内的不同波长，并从样本中检测到合理的回波幅度。
