化疗引起的周围神经病变的晚期癌症患者下尿路症状的影响因素
Factors Influencing Lower Urinary Tract Symptoms in Advanced Cancer Patients With Chemotherapy-Induced Peripheral Neuropathy.
作者信息
Cho Ok-Hee, Yoo Yang-Sook, Kim Joon Chul, Park Ran Hee, Hwang Kyung-Hye
机构信息
Department of Nursing, College of Nursing and Health, Kongju National University, Gongju, Korea.
College of Nursing, The Catholic University of Korea, Seoul, Korea.
出版信息
Int Neurourol J. 2018 Sep;22(3):192-199. doi: 10.5213/inj.1836084.042. Epub 2018 Sep 28.
PURPOSE
This study aimed to investigate the severity of lower urinary tract symptoms (LUTS) and to identify factors that influenced LUTS in advanced cancer patients with chemotherapy-induced peripheral neuropathy (CIPN).
METHODS
This cross-sectional study included a total of 158 advanced cancer patients with CIPN. A structured questionnaire including the International Prostate Symptom Score and the Functional Assessment of Cancer Therapy/Gynecology Oncology Group/Neurotoxicity scale was used. Data were analyzed using the Pearson correlation coefficient and multiple regression analysis.
RESULTS
Nocturia was the most prevalent LUTS. A positive relationship was found between CIPN symptoms and LUTS. The duration of cancer diagnosis and the severity of CIPN were key factors that influenced LUTS.
CONCLUSION
The severity of CIPN symptoms was the most important predictor of LUTS. Nurses' care for advanced cancer patients should incorporate a comprehensive health assessment, which includes a history of treatment and physical neuropathic symptoms, for any patient complaining of CIPN symptoms.
目的
本研究旨在调查晚期癌症患者化疗引起的周围神经病变（CIPN）时下尿路症状（LUTS）的严重程度，并确定影响LUTS的因素。
方法
这项横断面研究共纳入了158例患有CIPN的晚期癌症患者。使用了一份结构化问卷，包括国际前列腺症状评分和癌症治疗功能评估/妇科肿瘤学组/神经毒性量表。采用Pearson相关系数和多元回归分析对数据进行分析。
结果
夜尿症是最常见的LUTS。发现CIPN症状与LUTS之间存在正相关关系。癌症诊断时间和CIPN严重程度是影响LUTS的关键因素。
结论
CIPN症状的严重程度是LUTS最重要的预测因素。对于任何主诉CIPN症状的患者，护士对晚期癌症患者的护理应纳入全面的健康评估，包括治疗史和身体神经病变症状。
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