Han Chang Hoon, Kim Seung Jun, Chung Jae Ho
Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.
Department of Internal Medicine, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Republic of Korea.
Int Arch Allergy Immunol. 2018;177(4):334-341. doi: 10.1159/000491794. Epub 2018 Aug 21.
We explored the association between asthma severity and lower urinary tract symptoms (LUTS) using the International Prostate Symptom Score in a population-based study of males (aged ≥19 years) and evaluated voiding and urine storage symptoms.
This was a cross-sectional study of 101,848 males, 2,544 of whom had asthma, who participated in the 2011 Korean Community Health Survey. All subjects were assessed in terms of sociodemographic data, pre-existing conditions, and the presence of LUTS. Logistic regression was used to identify risk factors for LUTS in asthmatics.
Urine storage symptoms (frequency, urgency, and nocturia) and voiding symptoms (straining, a weak stream, intermittency, and incomplete emptying) were significantly higher in the asthma group than in the non-asthma group (all p < 0.001). Moderate and severe LUTS were significantly more common in the asthma group (moderate, 24.3%; severe, 22.5%) than in the nonasthma group (moderate, 9.5%; severe, 2.9%). Compared to the mild LUTS group, the odds ratio (OR) for asthma was 2.21 (95% confidence interval [CI] 1.99-2.46) in the moderate LUTS group, and 3.04 (95% CI 2.64-3.51) in the severe LUTS group. In a model evaluating multiple variables, the OR for asthma in the moderate LUTS group was 1.95 (95% CI 1.74-2.16) and that in the severe LUTS group was 2.17 (95% CI 1.87-2.53). Asthma was associated with both voiding and storage symptoms.
Male asthma was associated with moderate-to-severe LUTS. More aggressive urological diagnosis and treatment are needed for patients with asthma.
在一项基于人群的男性（年龄≥19岁）研究中，我们使用国际前列腺症状评分探讨哮喘严重程度与下尿路症状（LUTS）之间的关联，并评估排尿和储尿症状。
这是一项对101,848名男性进行的横断面研究，其中2544名患有哮喘，他们参与了2011年韩国社区健康调查。所有受试者均根据社会人口统计学数据、既往疾病情况和LUTS的存在情况进行评估。采用逻辑回归分析确定哮喘患者LUTS的危险因素。
哮喘组的储尿症状（尿频、尿急和夜尿）和排尿症状（用力排尿、尿流无力、间歇性排尿和排尿不尽）显著高于非哮喘组（所有p<0.001）。中度和重度LUTS在哮喘组（中度，24.3%；重度，22.5%）中比非哮喘组（中度，9.5%；重度，2.9%）更为常见。与轻度LUTS组相比，中度LUTS组哮喘的优势比（OR）为2.21（95%置信区间[CI]1.99 - 2.46），重度LUTS组为3.04（95%CI 2.64 - 3.51）。在评估多个变量的模型中，中度LUTS组哮喘的OR为1.95（95%CI 1.74 - 2.16），重度LUTS组为2.17（95%CI 1.87 - 2.53）。哮喘与排尿和储尿症状均有关联。
男性哮喘与中度至重度LUTS有关。哮喘患者需要更积极的泌尿外科诊断和治疗。
