功能行为为基础的认知行为疗法对自闭症谱系障碍儿童强迫行为的疗效：一项随机对照试验。
Functional Behavior-Based Cognitive-Behavioral Therapy for Obsessive Compulsive Behavior in Children with Autism Spectrum Disorder: A Randomized Controlled Trial.
机构信息
Departments of Child and Youth Studies and Applied Disability Studies, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.
Department of Applied Disability Studies, Brock University, St. Catharines, ON, Canada.
出版信息
J Autism Dev Disord. 2020 Jul;50(7):2375-2388. doi: 10.1007/s10803-018-3772-x.
Children with autism spectrum disorder (ASD) experience obsessions and compulsions similar to those specified in DSM-5 for obsessive compulsive disorder yet little controlled research exists on treating these behaviours. Thirty-seven children (7-13 years old) were randomly assigned to a 9-week functional behavior-based cognitive behavior therapy (Fb-CBT) or Treatment As Usual. Independent assessors administered measures pre- and post-treatment and at 6-months. Two primary outcome measures indicated statistically significant differences between groups, with large corrected effect sizes (Hedge's g = 1.00 and 1.15, respectively). This is the first known RCT to exclusively treat obsessive compulsive behaviors (OCBs) in children and youth with high functioning (IQ ≥ 70) ASD, and suggests that Fb-CBT treatment shows promise in decreasing these behaviors and improving quality of life. Trial Registration This trial was registered with ClinicalTrials.gov (ID: NCT03123146).
自闭症谱系障碍（ASD）儿童存在着强迫观念和强迫行为，与 DSM-5 中强迫症的规定类似，但针对这些行为的治疗方法却鲜有对照研究。37 名儿童（7-13 岁）被随机分配到为期 9 周的基于功能行为的认知行为疗法（Fb-CBT）或常规治疗组。独立评估者在治疗前、治疗后和 6 个月时进行了评估。两项主要的结果指标表明，两组之间存在统计学上的显著差异，具有较大的校正效应量（Hedge's g 分别为 1.00 和 1.15）。这是第一项专门针对高功能（智商≥70）自闭症儿童和青少年的强迫行为（OCBs）的 RCT 研究，表明 Fb-CBT 治疗在减少这些行为和提高生活质量方面具有一定的潜力。
试验注册
这项试验在 ClinicalTrials.gov 注册（ID：NCT03123146）。
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