Darrow W W, Echenberg D F, Jaffe H W, O'Malley P M, Byers R H, Getchell J P, Curran J W
Am J Public Health. 1987 Apr;77(4):479-83. doi: 10.2105/ajph.77.4.479.
To clarify risk factors for infection with the human immunodeficiency virus (HIV) we selected at random 785 homosexual men who had participated in studies of hepatitis B in San Francisco in 1978-80 for a follow-up study of the acquired immunodeficiency syndrome. Although most had not been contacted in over five years, 492 (63 per cent) were located and enrolled. The 240 (67 per cent) who had developed antibodies to HIV, as measured by an enzyme-linked immunosorbent assay (ELISA), were compared with 119 who had remained seronegative. In multivariate analyses, receptive anal intercourse with ejaculation by nonsteady sexual partners, many sexual partners per month, and other indicators of high levels of sexual activity were highly associated with seroconversions. None of the sexual practices that we studied appeared to offer protection against HIV infection.
为了阐明人类免疫缺陷病毒（HIV）感染的风险因素，我们随机选择了785名同性恋男性，他们曾在1978 - 1980年参与旧金山的乙型肝炎研究，以进行获得性免疫缺陷综合征的随访研究。尽管大多数人已有五年多未被联系过，但仍找到并招募了492人（63%）。通过酶联免疫吸附测定（ELISA）检测，已产生HIV抗体的240人（67%）与仍为血清阴性的119人进行了比较。在多变量分析中，与非固定性伴侣进行有射精的接受性肛交、每月有多个性伴侣以及其他高性活动水平指标与血清转化高度相关。我们研究的性行为中没有一种似乎能提供针对HIV感染的保护作用。
