二甲基亚砜在体外可诱导潜伏感染小鼠脾脏中的巨细胞病毒重新激活。简要报告。
DMSO induces reactivation of cytomegalovirus in vitro from spleens of latently infected mice. Brief report.
作者信息
Blackett S, Gupta A, Mims C A
出版信息
Arch Virol. 1987;93(3-4):273-8. doi: 10.1007/BF01310980.
PMID:3030239
Abstract
Reactivation of murine cytomegalovirus in spleen explant cultures from latently infected CD 1 mice was studied. A significant increase in the incidence of reactivation was observed when 200 mM DMSO was included in the culture medium. Virus could also be reactivated from the bone marrow of some mice.
摘要
对来自潜伏感染的CD1小鼠的脾外植体培养物中鼠巨细胞病毒的重新激活进行了研究。当培养基中加入200 mM二甲基亚砜（DMSO）时，观察到重新激活的发生率显著增加。病毒也可从一些小鼠的骨髓中重新激活。
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