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步行速度与全因死亡率和死因特异性死亡率降低相关。

Walking Pace Is Associated with Lower Risk of All-Cause and Cause-Specific Mortality.

机构信息

BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UNITED KINGDOM.

Institute of Health and Wellbeing, University of Glasgow, Glasgow, UNITED KINGDOM.

出版信息

Med Sci Sports Exerc. 2019 Mar;51(3):472-480. doi: 10.1249/MSS.0000000000001795.

DOI:10.1249/MSS.0000000000001795
PMID:30303933
Abstract

PURPOSE

Walking pace is associated with all-cause and cardiovascular disease (CVD) mortality. Whether this association extends to other health outcomes and whether it is independent of total amount of time walked are currently unknown. Therefore, the aim of this study was to investigate whether usual walking pace is associated with a range of health outcomes.

METHODS

UK Biobank participants (318,185 [54%] women) age 40 to 69 yr were included. Walking pace and total walking time were self-reported. The outcomes comprised: all-cause mortality as well as incidence and mortality from CVD, respiratory disease and cancer. The associations were investigated using Cox proportional hazard models.

RESULTS

Over a mean of 5.0 yr [ranging from 3.3 to 7.8], 5890 participants died, 18,568 developed CVD, 5430 respiratory disease and 19,234 cancer. In a fully adjusted model, compared to slow pace walkers, men and women, respectively, with a brisk pace having lower risk of mortality from all-causes (hazard ratio [HR], 0.79; 95% confidence interval [CI], 0.69-0.90 and HR, 0.73; 95% CI, 0.62-0.85), CVD (HR, 0.62; 95% CI, 0.50-0.76 and HR, 0.80; 95% CI, 0.73-0.88), respiratory disease (HR, 0.58; 95% CI, 0.43-0.78 and HR, 0.66; 95% CI, 0.57-0.77), chronic obstructive pulmonary disease (HR, 0.26; 95% CI, 0.12-0.56 and HR, 0.28; 95% CI, 0.16-0.49). No associations were found for all-cause cancer, colorectal, and breast cancer. However, brisk walking was associated with a higher risk of prostate cancer.

CONCLUSIONS

Walking pace is associated with lower risk of a wide range of important health conditions, independently of overall time spent walking.

摘要

目的

行走速度与全因死亡率和心血管疾病(CVD)死亡率相关。目前尚不清楚这种关联是否扩展到其他健康结果,以及它是否独立于行走的总时间。因此,本研究旨在调查通常的行走速度是否与一系列健康结果相关。

方法

纳入了英国生物库的参与者(318185[54%]名女性),年龄在 40 至 69 岁之间。行走速度和总行走时间均为自我报告。结果包括:全因死亡率以及 CVD、呼吸道疾病和癌症的发病率和死亡率。使用 Cox 比例风险模型进行关联研究。

结果

在平均 5.0 年(范围为 3.3 至 7.8 年)的随访中,5890 名参与者死亡,18568 名参与者发生 CVD,5430 名参与者发生呼吸道疾病,19234 名参与者发生癌症。在完全调整的模型中,与慢步快走者相比,男性和女性的快步快走者全因死亡率风险较低(风险比[HR],0.79;95%置信区间[CI],0.69-0.90 和 HR,0.73;95%CI,0.62-0.85),CVD(HR,0.62;95%CI,0.50-0.76 和 HR,0.80;95%CI,0.73-0.88),呼吸道疾病(HR,0.58;95%CI,0.43-0.78 和 HR,0.66;95%CI,0.57-0.77),慢性阻塞性肺疾病(HR,0.26;95%CI,0.12-0.56 和 HR,0.28;95%CI,0.16-0.49)。全因癌症、结直肠癌和乳腺癌与步行速度无关。然而,快步走与前列腺癌风险增加有关。

结论

行走速度与一系列重要健康状况的低风险相关,独立于总行走时间。

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