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实时动态血糖监测在 2 型糖尿病胰岛素治疗患者中的准确性。

Accuracy of flash glucose monitoring in insulin-treated patients with type 2 diabetes.

机构信息

Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.

Department ofCellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo, Japan.

出版信息

J Diabetes Investig. 2019 May;10(3):846-850. doi: 10.1111/jdi.12954. Epub 2018 Nov 12.

Abstract

The present study evaluated the accuracy of interstitial glucose measurements by flash glucose monitoring (FGM) and continuous glucose monitoring (CGM). Five diabetes patients simultaneously underwent FGM (FreeStyle Libre Pro) and CGM (iPro™2), and their glucose levels were compared with venous blood and capillary blood glucose levels. The range of daily venous blood glucose levels (30 measurements) was 70-245 mg/dL, with a median of 138 mg/dL. There were good correlations of glucose levels measured by FGM (r  = 0.90, mean absolute relative difference 8.2 ± 5.6%), CGM (r  = 0.86, mean absolute relative difference 9.2 ± 9.1%) and capillary blood (r  = 0.87, mean absolute relative difference 7.2 ± 7.2%) with venous blood glucose levels. The accuracy of FGM measurements was also shown against CGM, with 99.9% of the FGM values (1,279 measurements) being within the Parkes error grid zones A and B. The results suggest that the accuracy of FGM is similar to that of CGM, and that FGM is a useful tool for determining daily glucose profile.

摘要

本研究评估了通过瞬态血糖监测(FGM)和连续血糖监测(CGM)进行间质葡萄糖测量的准确性。五名糖尿病患者同时接受 FGM(FreeStyle Libre Pro)和 CGM(iPro™2)监测,并将其血糖水平与静脉血和毛细血管血糖水平进行比较。每日静脉血糖水平(30 次测量)范围为 70-245mg/dL,中位数为 138mg/dL。FGM(r=0.90,平均绝对相对差异 8.2±5.6%)、CGM(r=0.86,平均绝对相对差异 9.2±9.1%)和毛细血管血(r=0.87,平均绝对相对差异 7.2±7.2%)与静脉血血糖水平的相关性良好。FGM 测量的准确性也与 CGM 进行了比较,99.9%的 FGM 值(1279 次测量)在 Parkes 误差网格区 A 和 B 内。结果表明,FGM 的准确性与 CGM 相似,FGM 是确定日常血糖谱的有用工具。

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