12C2T - Centro de Ciência e Tecnologia Têxtil, Universidade do Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.
2Faculty of Textile and Clothing Technology, Niederrhein University of Applied Sciences, Webschulstrasse 31, 41065 Mönchengladbach, Germany.
Antimicrob Resist Infect Control. 2019 Aug 19;8:139. doi: 10.1186/s13756-019-0595-2. eCollection 2019.
"Ready-to-use" disinfecting wipes (also known as pre-impregnated disinfecting wipe) are broadly used in food industry and domestic situations. Their application in hospitals and healthcare centres for decontamination of medical devices and surfaces is steadily increasing because of their convenient implementation in practice and reliable performance. Beside their acceptable compliance and easy application, literature reported the disinfection failure due to the interaction between textile substrate and active ingredients, which can highly increase the risk of an infection outbreak. This review aims to call attention to the wide range of variables affecting the disinfectant-impregnated wipes' (DIWs) disinfection performances in hospitals.
A systematic literature search based on the five categories i. wipes, ii. disinfectants, iii. Application methods, iv. interaction between wipes and active ingredients and v. wiping strategy which can possibly influence the disinfection effectiveness of DIWs was conducted by Google scholar. Studies regarding the efficacy evaluation of DIWs in clinical applications were also reviewed from the National Centre for Biotechnology Information database.
Variables that impact on the disinfection performance of disinfectant-impregnated wipes in surface disinfection in hospitals were summarised and critically discussed. In addition to the information, current disinfectant-impregnated wipes' decontamination efficacy test standards were reviewed, and different standards exposed some disadvantage in their testing design.
Various parameters contribute to the impact of DIWs disinfection performance in practice. The interaction between disinfectant active ingredients and the wiping materials barricades their broad application in hospitals. More studies of the DIWs' disinfection efficacy in clinical practice are in need. Current standards evaluating the DIWs' efficacy are required to improve for more realistic condition simulation and differentiating between mechanical removal of inoculum from a surface and chemical inactivation of the test microbe.
“即用型”消毒湿巾（也称为预浸渍消毒湿巾）在食品工业和家庭环境中广泛使用。由于其在实践中的方便实施和可靠性能，它们在医院和医疗中心中用于医疗器械和表面的消毒的应用正在稳步增加。除了可接受的合规性和易于应用外，文献报道了由于纺织基底与有效成分之间的相互作用导致的消毒失败，这会极大地增加感染爆发的风险。本综述旨在引起人们对影响医院中浸渍消毒剂的消毒湿巾（DIWs）消毒性能的广泛变量的关注。
通过 Google Scholar 对五类 i. 湿巾、ii. 消毒剂、iii. 应用方法、iv. 湿巾和活性成分之间的相互作用以及 v. 擦拭策略进行了系统的文献检索，这些变量可能会影响 DIWs 的消毒效果。还从国家生物技术信息中心数据库中查阅了有关 DIWs 在临床应用中的功效评估的研究。
总结并批判性地讨论了影响医院表面消毒中浸渍消毒剂湿巾消毒性能的变量。除了信息外，还回顾了当前浸渍消毒剂湿巾去污功效测试标准，不同的标准在测试设计上存在一些缺点。
各种参数都会影响 DIWs 在实践中的消毒性能。消毒剂有效成分与擦拭材料之间的相互作用阻碍了其在医院中的广泛应用。需要更多关于 DIWs 在临床实践中消毒效果的研究。目前评估 DIWs 功效的标准需要改进，以更好地模拟现实条件，并区分从表面机械去除接种物和化学灭活测试微生物。
