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通过工业真菌增强生物质降解的新基因组学方法

New Genomic Approaches to Enhance Biomass Degradation by the Industrial Fungus .

作者信息

de Paula Renato Graciano, Antoniêto Amanda Cristina Campos, Ribeiro Liliane Fraga Costa, Carraro Cláudia Batista, Nogueira Karoline Maria Vieira, Lopes Douglas Christian Borges, Silva Alinne Costa, Zerbini Mariana Taíse, Pedersoli Wellington Ramos, Costa Mariana do Nascimento, Silva Roberto Nascimento

机构信息

Molecular Biotechnology Laboratory, Department of Biochemistry and Immunology, Ribeirao Preto Medical School (FMRP), University of Sao Paulo, Ribeirao Preto, SP, Brazil.

出版信息

Int J Genomics. 2018 Sep 24;2018:1974151. doi: 10.1155/2018/1974151. eCollection 2018.

DOI:10.1155/2018/1974151
PMID:30345291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6174759/
Abstract

The filamentous fungi is one of the most well-studied cellulolytic microorganisms. It is the most important fungus for the industrial production of enzymes to biomass deconstruction being widely used in the biotechnology industry, mainly in the production of biofuels. Here, we performed an analytic review of the holocellulolytic system presented by as well as the transcriptional and signaling mechanisms involved with holocellulase expression in this fungus. We also discuss new perspectives about control of secretion and cellulase expression based on RNA-seq and functional characterization data of growth in different carbon sources, which comprise glucose, cellulose, sophorose, and sugarcane bagasse.

摘要

丝状真菌是研究最为深入的纤维素分解微生物之一。它是工业生产用于生物质解构的酶的最重要真菌，在生物技术产业中广泛应用，主要用于生物燃料的生产。在此，我们对[具体真菌名称未给出]所呈现的全纤维素分解系统以及该真菌中与全纤维素酶表达相关的转录和信号传导机制进行了分析综述。我们还基于RNA测序以及[具体真菌名称未给出]在葡萄糖、纤维素、槐糖和甘蔗渣等不同碳源上生长的功能表征数据，讨论了关于分泌和纤维素酶表达调控的新观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/5f7f539b03a9/IJG2018-1974151.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/8a4980128a89/IJG2018-1974151.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/64b16bd86e27/IJG2018-1974151.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/63ec1a6f352c/IJG2018-1974151.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/921edd47e8d7/IJG2018-1974151.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/62f45b5af636/IJG2018-1974151.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/e8df871c3c21/IJG2018-1974151.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/5f7f539b03a9/IJG2018-1974151.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/8a4980128a89/IJG2018-1974151.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/64b16bd86e27/IJG2018-1974151.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/63ec1a6f352c/IJG2018-1974151.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/921edd47e8d7/IJG2018-1974151.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/62f45b5af636/IJG2018-1974151.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/e8df871c3c21/IJG2018-1974151.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b2f/6174759/5f7f539b03a9/IJG2018-1974151.007.jpg

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