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尼帕病的主要危险因素及其在中国的风险分析。

The Main Risk Factors of Nipah Disease and Its Risk Analysis in China.

机构信息

Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Taian 271018, China.

China Center for Animal Health and Epidemiology, Qingdao 266000, China.

出版信息

Viruses. 2018 Oct 19;10(10):572. doi: 10.3390/v10100572.

DOI:10.3390/v10100572
PMID:30347642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6213763/
Abstract

Nipah disease is a highly fatal zoonosis which is caused by the Nipah virus. The Nipah virus is a BSL-4 virus with fruit bats being its natural host. It is mainly prevalent in Southeast Asia. The virus was first discovered in 1997 in Negeri Sembilan, Malaysia. Currently, it is mainly harmful to pigs and humans with a high mortality rate. This study describes the route of transmission of the Nipah virus in different countries and analyzes the possibility of the primary disease being in China and the method of its transmission to China. The risk factors are analyzed for different susceptible populations to Nipah disease. The aim is to improve people's risk awareness and prevention and control of the disease and reduce its risk of occurring and spreading in China.

摘要

尼帕病毒病是一种由尼帕病毒引起的高致命性人畜共患病。尼帕病毒是一种 BSL-4 病毒,其天然宿主是果蝠。它主要流行于东南亚。该病毒于 1997 年在马来西亚森美兰州首次被发现。目前,它主要对猪和人类有害,死亡率很高。本研究描述了尼帕病毒在不同国家的传播途径,并分析了该病原发地在中国的可能性及其传入中国的方式。对不同易感人群感染尼帕病的危险因素进行了分析。目的是提高人们对该病的风险意识和防控能力,降低其在中国发生和传播的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/ba62237ff699/viruses-10-00572-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/66560c134d00/viruses-10-00572-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/b20a4d5ca0f8/viruses-10-00572-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/e5452df3e45a/viruses-10-00572-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/2a86edd29768/viruses-10-00572-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/29f77a7654a1/viruses-10-00572-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/ba62237ff699/viruses-10-00572-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/66560c134d00/viruses-10-00572-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/b20a4d5ca0f8/viruses-10-00572-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/e5452df3e45a/viruses-10-00572-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/2a86edd29768/viruses-10-00572-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/29f77a7654a1/viruses-10-00572-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8680/6213763/ba62237ff699/viruses-10-00572-g006.jpg

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本文引用的文献

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Nipah virus: transmission of a zoonotic paramyxovirus.尼帕病毒:一种人畜共患副粘病毒的传播
Curr Opin Virol. 2017 Feb;22:97-104. doi: 10.1016/j.coviro.2016.12.003. Epub 2017 Jan 11.
2
Investigating Rare Risk Factors for Nipah Virus in Bangladesh: 2001-2012.孟加拉国2001 - 2012年尼帕病毒罕见风险因素调查
Ecohealth. 2016 Dec;13(4):720-728. doi: 10.1007/s10393-016-1166-0. Epub 2016 Oct 13.
3
Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy.在灵长类动物中尼帕病毒孟加拉国和马来西亚株的致病差异:对抗体治疗的影响。
尼帕病毒:流行病学、病理学、免疫生物学以及在诊断、疫苗设计和控制策略方面的进展 - 全面综述。
Vet Q. 2019 Dec;39(1):26-55. doi: 10.1080/01652176.2019.1580827.
Sci Rep. 2016 Aug 3;6:30916. doi: 10.1038/srep30916.
4
Taxonomy of the order Mononegavirales: update 2016.单股负链RNA病毒目分类:2016年更新
Arch Virol. 2016 Aug;161(8):2351-60. doi: 10.1007/s00705-016-2880-1. Epub 2016 May 23.
5
Nipah Virus Transmission from Bats to Humans Associated with Drinking Traditional Liquor Made from Date Palm Sap, Bangladesh, 2011-2014.2011 - 2014年,孟加拉国尼帕病毒从蝙蝠传播至人类与饮用由椰枣汁制成的传统酒有关
Emerg Infect Dis. 2016 Apr;22(4):664-70. doi: 10.3201/eid2204.151747.
6
Origin and evolution of Nipah virus.尼帕病毒的起源与演化。
J Med Virol. 2016 Mar;88(3):380-8. doi: 10.1002/jmv.24345. Epub 2015 Aug 14.
7
Spatial characterization of colonies of the flying fox bat, a carrier of Nipah virus in Thailand.泰国尼帕病毒携带者——飞狐蝠群落的空间特征
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Outbreak of henipavirus infection, Philippines, 2014.2014年菲律宾亨尼帕病毒感染疫情
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Evidence for henipavirus spillover into human populations in Africa.亨尼帕病毒传播至非洲人群的证据。
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