Raveendran Arkiath V, Chacko Elias C, Pappachan Joseph M
Badr Al Samaa, Barka, Sultanate of Oman.
Department of Endocrinology, Jersey General Hospital, Jersey.
Eur Endocrinol. 2018 Sep;14(2):31-39. doi: 10.17925/EE.2018.14.2.31. Epub 2018 Sep 10.
The global prevalence of diabetes, especially type 2 diabetes mellitus, has reached epidemic proportions in the last few decades of the 20th century because of the obesity pandemic resulting from adverse lifestyles. Diabetes as a consequence of obesity (diabesity), continues to increase exponentially in the 21st century. Although there are a multitude of drugs for the effective management of diabesity with modest benefits, most patients will require insulin for control of diabetes at some stage that would worsen obesity, and thereby diabesity. Therefore, effective non-pharmacological therapy needs to be expedited in all patients with diabesity. These measures include medical nutrition interventions, change of lifestyles and bariatric surgery. Non-pharmacological interventions are also useful for the effective management of even type 1 diabetes mellitus when used along with insulin therapy especially in those with obesity. This review summarises the current evidence base for the non-pharmacological interventions in the management of diabetes.
在20世纪的最后几十年里，由于不良生活方式导致肥胖症流行，全球糖尿病，尤其是2型糖尿病的患病率已达到流行程度。肥胖导致的糖尿病（糖尿病肥胖症）在21世纪继续呈指数级增长。尽管有多种药物可有效管理糖尿病肥胖症且有一定益处，但大多数患者在某个阶段仍需要胰岛素来控制糖尿病，而这会加重肥胖，进而加重糖尿病肥胖症。因此，需要加快对所有糖尿病肥胖症患者进行有效的非药物治疗。这些措施包括医学营养干预、生活方式改变和减肥手术。非药物干预与胰岛素治疗一起使用时，对有效管理1型糖尿病也很有用，尤其是对肥胖患者。本综述总结了糖尿病管理中非药物干预的当前证据基础。
