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慢性阻塞性肺疾病评估测试(CAT)在特发性肺纤维化患者中的验证

Validation of the COPD Assessment Test (CAT) in patients with idiopathic pulmonary fibrosis.

作者信息

Grufstedt Heidi Kjeldgaard, Shaker Saher Burhan, Konradsen Hanne

机构信息

Department of Respiratory Medicine, Gentofte University Hospital, Hellerup, Denmark.

Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institut NVS, Huddinge, Sweden.

出版信息

Eur Clin Respir J. 2018 Oct 16;5(1):1530028. doi: 10.1080/20018525.2018.1530028. eCollection 2018.

DOI:10.1080/20018525.2018.1530028
PMID:30357006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6197013/
Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic disease with high morbidity and mortality. A reliable and manageable questionnaire that assesses patients' quality of life is needed to help to improve the content of clinical consultations. The chronic obstructive pulmonary disease (COPD) Assessment Test (CAT) is used in clinical practice; therefore, the aim of this study was to investigate correlations among the CAT, St. George's Respiratory Questionnaire (SGRQ) and clinical parameters among patients diagnosed with IPF. A retrospective cohort design was employed in which 87 patients diagnosed with IPF who were receiving treatment at an outpatient clinic were included. The CAT was found to be significantly correlated with SGRQ ( < 0.001). Furthermore, the CAT was significantly correlated with all of the included physiological variables. This add to support the validity of the COPD Assessment test (CAT) as a measure of symptoms in patients with IPF which in clinical practice in combination with dialogue between healthcare professionals and the patient, can help to improve the content of a clinical consultation.

摘要

特发性肺纤维化(IPF)是一种发病率和死亡率都很高的慢性疾病。需要一个可靠且易于管理的问卷来评估患者的生活质量,以帮助改善临床会诊的内容。慢性阻塞性肺疾病(COPD)评估测试(CAT)已应用于临床实践;因此,本研究的目的是调查确诊为IPF的患者中CAT、圣乔治呼吸问卷(SGRQ)与临床参数之间的相关性。本研究采用回顾性队列设计,纳入了87例在门诊接受治疗的确诊为IPF的患者。研究发现,CAT与SGRQ显著相关(<0.001)。此外,CAT与所有纳入的生理变量均显著相关。这进一步支持了COPD评估测试(CAT)作为IPF患者症状衡量指标的有效性,在临床实践中,结合医护人员与患者之间的沟通,CAT有助于改善临床会诊的内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/c248c7a74327/ZECR_A_1530028_F0003_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/65a08313d911/ZECR_A_1530028_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/5b049eb607f0/ZECR_A_1530028_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/c248c7a74327/ZECR_A_1530028_F0003_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/65a08313d911/ZECR_A_1530028_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/5b049eb607f0/ZECR_A_1530028_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b32/6197013/c248c7a74327/ZECR_A_1530028_F0003_B.jpg

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Acute Exacerbation of Idiopathic Pulmonary Fibrosis. An International Working Group Report.特发性肺纤维化急性加重:国际工作组报告。
Am J Respir Crit Care Med. 2016 Aug 1;194(3):265-75. doi: 10.1164/rccm.201604-0801CI.
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Incidence and prevalence of idiopathic pulmonary fibrosis in US adults 18-64 years old.
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Adverse Effects, Smoking, Alcohol Consumption, and Quality of Life during Long-Term Oxygen Therapy: A Nationwide Study.长期氧疗期间的不良反应、吸烟、饮酒与生活质量:一项全国性研究。
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