韩国绝经期后妇女的抑郁及其与健康相关生活质量的关系。
Depression and Its Association with Health-Related Quality of Life in Postmenopausal Women in Korea.
机构信息
Department of International Healthcare Administration, Daegu Catholic University, Gyeongsan 38430, Korea.
College of Pharmacy, Keimyung University, Daegu Metropolitan 42601, Korea.
出版信息
Int J Environ Res Public Health. 2018 Oct 23;15(11):2327. doi: 10.3390/ijerph15112327.
Menopause is associated with depressive symptoms that can significantly affect a woman's quality of life. The objective of this study was to evaluate the association between depression and health-related quality of life (HRQoL) in postmenopausal women. In this cross-sectional descriptive study, participants ( = 3860) were selected from the 2013⁻2015 Korea National Health and Nutrition Examination Survey (KNHANES). The sociodemographic characteristics, medical history of depression, and EQ-5D scores of the participants were obtained from the KNHANES dataset. Age, educational level, and income were associated with HRQoL in these participants. Moreover, depression exerted a considerable influence on HRQoL in postmenopausal women. The adjusted odds ratios in participants with depression for the EQ-5D dimensions were as follows: 5.52 (95% CI = 4.04⁻7.55, < 0.001) for anxiety/depression, 3.86 (95% CI = 2.78⁻5.36, < 0.001) for usual activities, and 2.52 (95% CI = 1.68⁻3.78, < 0.001) for self-care. Our findings suggest a strong association between depression and HRQoL. Hence, preventing the onset or exacerbation of depression may significantly improve quality of life in postmenopausal women.
绝经与抑郁症状相关，这些症状会显著影响女性的生活质量。本研究旨在评估绝经后妇女抑郁与健康相关生活质量（HRQoL）之间的关系。在这项横断面描述性研究中，参与者（n=3860）是从 2013-2015 年韩国国家健康和营养检查调查（KNHANES）中选取的。参与者的社会人口统计学特征、抑郁病史和 EQ-5D 评分均来自 KNHANES 数据集。年龄、教育水平和收入与这些参与者的 HRQoL 相关。此外，抑郁对绝经后妇女的 HRQoL 有很大影响。患有抑郁的参与者在 EQ-5D 各维度的调整后比值比（OR）分别为：焦虑/抑郁（95%CI=4.04-7.55， < 0.001）、日常活动（95%CI=2.78-5.36， < 0.001）和自我护理（95%CI=1.68-3.78， < 0.001）。我们的研究结果表明，抑郁与 HRQoL 之间存在密切关联。因此，预防抑郁的发生或加重可能会显著提高绝经后妇女的生活质量。
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