Instituto de Salud de la Mujer. Hospital Clinico San Carlos, IdISSC, Complutense University, Madrid, Spain.
Department of Obstetrics and Gynecology, Hospital Sanitas La Zarzuela, Universidad Franscisco de Vitoria, Madrid, Spain.
Maturitas. 2021 Feb;144:4-10. doi: 10.1016/j.maturitas.2020.09.004. Epub 2020 Sep 28.
To assess the impact of confinement due to the coronavirus (Covid-19) pandemic on health-related quality of life (HRQoL) and resilience in peri- and postmenopausal women.
We used an online questionnaire which was sent between April 30th and May 13th, 2020 to women aged 40-70 years who were peri- or postmenopausal according to STRAW criteria. We used the 16-item Cervantes short-form scale (Cervantes-SF) to measure HRQoL, and the 14-item Wagnild and Young Resilience Scale (RS-14) to measure resilience. High scores on the Cervantes-SF indicate low HRQoL and high scores on the RS-14 indicate high levels of resilience. Covid-19 status, sociodemographic descriptors, and lifestyle variables were also evaluated.
We included 2430 peri- and postmenopausal women with valid questionnaires. All items of the Cervantes-SF were completed in 2151 cases, whilst the RS-14 was completed in 2413 cases. There was a negative correlation between scores on the Cervantes-SF and RS-14 scales (Rho -0.350; p < 0.0001). Multiple linear regression analysis revealed a statistically significant association between Cervantes-SF scores and living with others (β-coefficient -10.2; p < 0.001), use of antidepressants (β 9.3; p < 0.001), physical activity (β -8.6; p < 0.001) and sexual activity (β -2.7; p < 0.001). Resilience was associated with the use of antidepressants (β -5.9; p < 0.001), physical activity (β 3.2; p < 0.001) and sexual activity (β 1.7; p = 0.005). According to the multivariate analysis, there were no associations between either Covid-19 or menopausal status and HRQoL or resilience scores.
During the period of mandatory Covid-19 confinement, peri- and postmenopausal women who engaged in physical and sexual activity had higher HRQoL and higher levels of resilience, whilst women who were using antidepressants had lower HRQoL and lower levels of resilience. HRQoL was greater in women who lived with others.
评估因冠状病毒（Covid-19）大流行而导致的禁闭对围绝经期和绝经后妇女的健康相关生活质量（HRQoL）和适应力的影响。
我们使用了一种在线问卷，该问卷于 2020 年 4 月 30 日至 5 月 13 日之间发送给根据 STRAW 标准处于围绝经期或绝经后的 40-70 岁妇女。我们使用 16 项 Cervantes 短式量表（Cervantes-SF）来衡量 HRQoL，使用 14 项 Wagnild 和 Young 适应力量表（RS-14）来衡量适应力。Cervantes-SF 的高分表示 HRQoL 较低，而 RS-14 的高分表示适应力较高。还评估了 Covid-19 状况，社会人口统计学描述符和生活方式变量。
我们纳入了 2430 名具有有效问卷的围绝经期和绝经后妇女。Cervantes-SF 的所有项目均在 2151 例中完成，而 RS-14 则在 2413 例中完成。Cervantes-SF 和 RS-14 量表的评分之间呈负相关（Rho-0.350；p<0.0001）。多元线性回归分析显示，Cervantes-SF 评分与与他人同住（β系数-10.2；p<0.001），使用抗抑郁药（β9.3；p<0.001），身体活动（β-8.6；p<0.001）和性活动（β-2.7；p<0.001）之间存在统计学显著关联。适应力与使用抗抑郁药（β-5.9；p<0.001），身体活动（β3.2；p<0.001）和性活动（β1.7；p=0.005）有关。根据多变量分析，Covid-19 或绝经状态与 HRQoL 或适应力评分之间均无关联。
在强制性的 Covid-19 禁闭期间，进行身体和性活动的围绝经期和绝经后妇女的 HRQoL 更高，适应力更高，而使用抗抑郁药的妇女的 HRQoL 更低，适应力更低。与他人同住的妇女的 HRQoL 更高。
