Ehteshami Mehdi, Shakerhosseini Rahebeh, Sedaghat Fatemeh, Hedayati Mehdi, Eini-Zinab Hassan, Hekmatdoost Azita
Department of Clinical Nutrition and Dietetics,, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Email:
Asian Pac J Cancer Prev. 2018 Oct 26;19(10):2979-2984. doi: 10.22034/APJCP.2018.19.10.2979.
Background: This study aimed to assess the effects of Gluten free diet (GFD) on components of metabolic syndrome (MES). Materials and Methods: In this randomized clinical trial, 50 subjects diagnosed with MES were randomly divided into two groups (n=25). The first group received a GFD and the second group continued their regular diet. Biochemical markers of MES and blood pressure were measured before and after 8-week intervention. Results: Forty five subjects completed the study. A post-hoc comparison of the groups showed no effects of the GFD and control diet on LDL cholesterol, total cholesterol, fasting insulin, HOMA-IR, systolic and diastolic blood pressure levels. The GFD reduced fasting blood glucose, waist circumference (WC) and serum triglyceride concentration significantly compared with the control diet (p<0.05). Conclusion: Short-term GFD reduced WC and improved glycemic control and Triglyceride level in subjects with the metabolic syndrome.
本研究旨在评估无麸质饮食（GFD）对代谢综合征（MES）各组分的影响。
在这项随机临床试验中，50名被诊断为MES的受试者被随机分为两组（n = 25）。第一组接受无麸质饮食，第二组继续其常规饮食。在8周干预前后测量MES的生化指标和血压。
45名受试者完成了研究。两组的事后比较显示，无麸质饮食和对照饮食对低密度脂蛋白胆固醇、总胆固醇、空腹胰岛素、HOMA-IR、收缩压和舒张压水平均无影响。与对照饮食相比，无麸质饮食显著降低了空腹血糖、腰围（WC）和血清甘油三酯浓度（p<0.05）。
短期无麸质饮食可降低代谢综合征患者的腰围，改善血糖控制和甘油三酯水平。
