特定抑制性T细胞的富集及其表面标志物的表征。
Enrichment of specific suppressor T cells and characterization of their surface markers.
作者信息
Taniguchi M, Miller J F
出版信息
J Exp Med. 1977 Nov 1;146(5):1450-4. doi: 10.1084/jem.146.5.1450.
Abstract
A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specific for the I-J subregion gene product in the presence of complement.
摘要
本文描述了一种简单的方法，该方法可使抗原特异性抑制性T细胞富集超过100倍。富集的细胞具有以下特征性标志物：Ig-、Thy-1+、Ly-1-、Ly-2,3+和I-J+。在补体存在的情况下，超过30%的这群细胞可被针对I-J亚区基因产物的抗血清直接杀伤。
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