遭受移植物抗宿主反应的小鼠体内产生的抑制性T细胞的Ly表型。
The Ly phenotype of suppressor T cells arising in mice subjected to a graft-versus-host reaction.
作者信息
Pickel K, Hoffmann M K
出版信息
J Exp Med. 1977 May 1;145(5):1169-75. doi: 10.1084/jem.145.5.1169.
Abstract
T cells with helper and suppressor functions arising during graft-versus-host reaction (B6 vs. BDF1) have been characterized with respect to their Ly surface antigens. Helper cells were found to express the phenotype Ly 1+2- and suppressor cells the phenotype Ly 1+2+. Ly 1-2+ T cells had no suppressive effect in this system. T cells of the host did not contribute to either activity.
摘要
在移植物抗宿主反应（B6对BDF1）过程中产生的具有辅助和抑制功能的T细胞，已根据其Ly表面抗原进行了表征。发现辅助性细胞表达Ly 1+2-表型，而抑制性细胞表达Ly 1+2+表型。Ly 1-2+ T细胞在该系统中没有抑制作用。宿主的T细胞对这两种活性均无贡献。
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