Pulmonary Center, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02115, USA.
Clin Chest Med. 2018 Dec;39(4):669-676. doi: 10.1016/j.ccm.2018.07.002.
Pneumonia is an important cause of morbidity and mortality. However, pneumonia is an unusual outcome of respiratory infection. Most of the time, microbes in the lung can be controlled by a combination of constitutive and recruited defense mechanisms. Inflammation is a key component of recruited defenses. Variations in inflammation that influence pneumonia susceptibility and severity are considered here.
肺炎是发病率和死亡率的重要原因。然而,肺炎是呼吸道感染的一种不常见的结果。大多数时候,肺部的微生物可以通过组成性和募集的防御机制的组合来控制。炎症是募集防御的关键组成部分。在这里考虑影响肺炎易感性和严重程度的炎症变化。