用吲哚美辛或肉桂酸功能化的杂化安德森六钼酸铝（III）的合成与表征
Synthesis and characterization of hybrid Anderson hexamolybdoaluminates(III) functionalized with indometacin or cinnamic acid.
作者信息
Gumerova Nadiia I, Blazevic Amir, Caldera Fraile Tania, Roller Alexander, Giester Gerald, Rompel Annette
机构信息
Universität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, Althanstrasse 14, Wien 1090, Austria.
Universität Wien, Facultät für Chemie, Zentrum für Röntgenstrukturanalyse, Währinger Strasse 42, Wien 1090, Austria.
出版信息
Acta Crystallogr C Struct Chem. 2018 Nov 1;74(Pt 11):1378-1383. doi: 10.1107/S2053229618012536. Epub 2018 Oct 24.
The single-side Al-centred tris-functionalized hybrid organic-inorganic Anderson polyoxomolybdates (CHN)[Al(OH)MoO(OCH)CNH(CHO)]·CHN·4CHOH·5HO (AlMo-NH-Cin; Cin is cinnamic acid, CHO) and (CHN)[Al(OH)MoO(OCH)CNH(CHClNO)]·9HO (AlMo-NH-Indo; Indo is indometacin, CHClNO) have been prepared in a mild three-step synthesis and structurally characterized by single-crystal X-ray diffraction, H NMR and IR spectroscopies and elemental analysis. Both AlMo-NH-Cin and AlMo-NH-Indo crystallize in the orthorhombic space group Pbca. The antibacterial activities of AlMo-NH-Cin and AlMo-NH-Indo against the Gram-negative human mucosal pathogen Moraxella catarrhalis were investigated by determination of the minimum inhibitory concentration, which is 32 µg ml for AlMo-NH-Cin and 256 µg ml for AlMo-NH-Indo.
通过温和的三步合成法制备了单侧以铝为中心的三官能化杂化有机-无机安德森多钼酸盐（(CH₃NH₃)₂[Al(OH)Mo₆O₁₈(OCH₃)₂(CNH₂)(C₆H₅CHO)]·CH₃NH₃·4CH₃OH·5H₂O （AlMo-NH-Cin；Cin为肉桂酸，C₆H₅CHO））和((CH₃NH₃)₂[Al(OH)Mo₆O₁₈(OCH₃)₂(CNH₂)(C₁₉H₁₉ClNO₂)]·9H₂O （AlMo-NH-Indo；Indo为吲哚美辛，C₁₉H₁₉ClNO₂）），并通过单晶X射线衍射、¹H NMR和红外光谱以及元素分析对其结构进行了表征。AlMo-NH-Cin和AlMo-NH-Indo均结晶于正交空间群Pbca中。通过测定最低抑菌浓度，研究了AlMo-NH-Cin和AlMo-NH-Indo对革兰氏阴性人类黏膜病原体卡他莫拉菌的抗菌活性，AlMo-NH-Cin的最低抑菌浓度为32 μg/ml，AlMo-NH-Indo的最低抑菌浓度为256 μg/ml。
Zotero 插件