Chinese Academy of Sciences, Yantai Institute of Coastal Zone Research , Yantai , China.
Nat Prod Res. 2019 Nov;33(21):3127-3133. doi: 10.1080/14786419.2018.1522314. Epub 2018 Nov 6.
Three cyclonerane sesquiterpenoids, including the known cyclonerodiol (), together with its new derivatives, (10)-12-acetoxy-10-cycloneren-3,7 -diol () and 12-acetoxycycloneran-3,7-diol () were isolated from the cultures of marine-sediment-derived fungus P1-4. The structures of the new compounds ( and ) were elucidated based on extensive spectroscopic methods (1D/2D NMR and HR-MS) and optical rotation analysis.
从海洋沉积物来源的真菌 P1-4 的培养物中分离得到三种环罗勒烯倍半萜，包括已知的环罗勒二醇 ()，以及它的新衍生物 (10)-12-乙酰氧基-10-环罗勒烯-3,7-二醇 () 和 12-乙酰氧基环罗勒烯-3,7-二醇 ()。新化合物 () 的结构是通过广泛的光谱方法 (1D/2D NMR 和 HR-MS) 和旋光分析确定的。
