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基于微流控技术的利用人工细菌鞭毛进行液滴和细胞操控

Microfluidic-Based Droplet and Cell Manipulations Using Artificial Bacterial Flagella.

作者信息

Ding Yun, Qiu Famin, Casadevall I Solvas Xavier, Chiu Flora Wing Yin, Nelson Bradley J, deMello Andrew

机构信息

Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir Prelog Weg 1, 8093 Zürich, Switzerland.

Institute for Robotics and Intelligent Systems, ETH Zürich, Tannenstrasse 3, 8092 Zürich, Switzerland.

出版信息

Micromachines (Basel). 2016 Feb 8;7(2):25. doi: 10.3390/mi7020025.

DOI:10.3390/mi7020025
PMID:30407399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6190376/
Abstract

Herein, we assess the functionality of magnetic helical microswimmers as basic tools for the manipulation of soft materials, including microdroplets and single cells. Their ability to perform a range of unit operations is evaluated and the operational challenges associated with their use are established. In addition, we also report on interactions observed between the head of such helical swimmers and the boundaries of droplets and cells and discuss the possibilities of assembling an artificial swimming microorganism or a motorized cell.

摘要

在此，我们评估磁性螺旋微游动器作为操纵软材料（包括微滴和单细胞）的基本工具的功能。评估了它们执行一系列单元操作的能力，并确定了与它们的使用相关的操作挑战。此外，我们还报告了在此类螺旋游动器头部与液滴和细胞边界之间观察到的相互作用，并讨论了组装人工游动微生物或机动细胞的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/67a58d6c22e8/micromachines-07-00025-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/35dfe8844092/micromachines-07-00025-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/d1bdcef17cac/micromachines-07-00025-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/3f1c39dd84df/micromachines-07-00025-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/ec8818af2f81/micromachines-07-00025-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/f708c56f4d45/micromachines-07-00025-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/7dd88dfc129d/micromachines-07-00025-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/7dd6a0bdeb3e/micromachines-07-00025-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/67a58d6c22e8/micromachines-07-00025-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/35dfe8844092/micromachines-07-00025-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/d1bdcef17cac/micromachines-07-00025-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/3f1c39dd84df/micromachines-07-00025-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/ec8818af2f81/micromachines-07-00025-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/f708c56f4d45/micromachines-07-00025-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/7dd88dfc129d/micromachines-07-00025-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/7dd6a0bdeb3e/micromachines-07-00025-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a239/6190376/67a58d6c22e8/micromachines-07-00025-g008.jpg

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