European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Nucleic Acids Res. 2019 Jan 8;47(D1):D745-D751. doi: 10.1093/nar/gky1113.
The Ensembl project (https://www.ensembl.org) makes key genomic data sets available to the entire scientific community without restrictions. Ensembl seeks to be a fundamental resource driving scientific progress by creating, maintaining and updating reference genome annotation and comparative genomics resources. This year we describe our new and expanded gene, variant and comparative annotation capabilities, which led to a 50% increase in the number of vertebrate genomes we support. We have also doubled the number of available human variants and added regulatory regions for many mouse cell types and developmental stages. Our data sets and tools are available via the Ensembl website as well as a through a RESTful webservice, Perl application programming interface and as data files for download.
Ensembl 项目(https://www.ensembl.org)向整个科学界提供关键的基因组数据集,没有任何限制。Ensembl 旨在通过创建、维护和更新参考基因组注释和比较基因组资源,成为推动科学进步的基础资源。今年,我们描述了我们新的和扩展的基因、变体和比较注释功能,这使得我们支持的脊椎动物基因组数量增加了 50%。我们还将可用的人类变体数量增加了一倍,并为许多小鼠细胞类型和发育阶段添加了调控区域。我们的数据集和工具可通过 Ensembl 网站以及通过基于 REST 的 Web 服务、Perl 应用程序编程接口以及作为可下载的数据文件获得。