European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, USA.
Nucleic Acids Res. 2022 Jan 7;50(D1):D996-D1003. doi: 10.1093/nar/gkab1007.
Ensembl Genomes (https://www.ensemblgenomes.org) provides access to non-vertebrate genomes and analysis complementing vertebrate resources developed by the Ensembl project (https://www.ensembl.org). The two resources collectively present genome annotation through a consistent set of interfaces spanning the tree of life presenting genome sequence, annotation, variation, transcriptomic data and comparative analysis. Here, we present our largest increase in plant, metazoan and fungal genomes since the project's inception creating one of the world's most comprehensive genomic resources and describe our efforts to reduce genome redundancy in our Bacteria portal. We detail our new efforts in gene annotation, our emerging support for pangenome analysis, our efforts to accelerate data dissemination through the Ensembl Rapid Release resource and our new AlphaFold visualization. Finally, we present details of our future plans including updates on our integration with Ensembl, and how we plan to improve our support for the microbial research community. Software and data are made available without restriction via our website, online tools platform and programmatic interfaces (available under an Apache 2.0 license). Data updates are synchronised with Ensembl's release cycle.
Ensembl Genomes（https://www.ensemblgenomes.org）提供了非脊椎动物基因组的访问和分析，这些资源补充了由 Ensembl 项目（https://www.ensembl.org）开发的脊椎动物资源。这两个资源通过跨越生命之树的一致接口集共同呈现基因组注释，包括基因组序列、注释、变异、转录组数据和比较分析。在这里，我们展示了自项目启动以来植物、后生动物和真菌基因组的最大增长，创建了世界上最全面的基因组资源之一，并描述了我们在细菌门户中减少基因组冗余的努力。我们详细介绍了我们在基因注释方面的新努力、我们对泛基因组分析的新兴支持、我们通过 Ensembl Rapid Release 资源加速数据传播的努力以及我们新的 AlphaFold 可视化。最后，我们介绍了我们未来的计划细节，包括与 Ensembl 集成的更新，以及我们计划如何改进对微生物研究社区的支持。软件和数据可通过我们的网站、在线工具平台和编程接口（根据 Apache 2.0 许可证）无限制地提供。数据更新与 Ensembl 的发布周期同步。
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