Department of Pediatrics, Maasstad Hospital, Room 1F2042, PO box 9100, 3007 AC, Rotterdam, The Netherlands.
Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, dr. Molenwaterplein 60, 3015 GJ, Rotterdam, The Netherlands.
Eur J Pediatr. 2019 Feb;178(2):229-234. doi: 10.1007/s00431-018-3285-9. Epub 2018 Nov 9.
Pediatric Early Warning Scores were developed to monitor clinical deterioration of children admitted to the hospital. Pediatric Early Warning Scores could also be useful in the Emergency Department to quickly identify critically ill patients so treatment can be started without delay. To determine if a newly designed, fast, and easy to use Modified Pediatric Early Warning Score can identify critically ill children in the Emergency Department. We conducted a retrospective observational study in the Emergency Department of an urban district hospital in Rotterdam, the Netherlands. Patients < 16 years attending the Emergency Department with an internal medical problem were included. Immediate intensive care unit admission was used as a measure for critically ill children. During the study period 2980 children attended the Emergency Department, ten (0.4%) of them required immediate intensive care unit admission. The Modified Pediatric Early Warning Score can identify critically ill children in the general pediatric Emergency Department population (area under the ROC curve 0.82). A sensitivity of 80% and specificity of 85% show potential to rule out critical illness in children visiting the Emergency Department when these results are validated in a larger population. A model containing both the Modified Pediatric Early Warning Score and the Manchester Triage System did not perform significantly better than the Manchester Triage System alone but did show a positive tendency in favor of the model containing the Modified Pediatric Early Warning Score and Manchester Triage System, area under the ROC curve 0.89 [95% CI 0.77-1.00] versus area under the ROC curve 0.82 [95% CI 0.68-0.95].Conclusions: In this feasibility study, the Modified Pediatric Early Warning Score could be a fast and easy to use tool to identify critically ill children in the general pediatric Emergency Department population. The effectiveness of the Modified Pediatric Early Warning Score may be optimized if combined with triage systems such as the Manchester Triage System. A larger prospective study is needed to confirm our results. What is known: • Pediatric Early Warning Scores can identify children who are in need for immediate intensive care unit admission at the Emergency Department. • Pediatric Early Warning Scores can be time-consuming, contain subjective parameters or parameters which are difficult to obtain in a reliable and standardized method. What is new: • We introduce a simplified, manageable and smartly designed Pediatric Early Warning Score on a pocket card based on an existing and previously investigated Pediatric Early Warning Score. • In this feasibility study the diagnostic performance of the Modified Pediatric Early Warning Score to predict immediate intensive care unit admission in the Emergency Department is in line with the original Pediatric Early Warning Scores but has to be validated on a larger scale.
儿科早期预警评分旨在监测住院患儿的临床恶化情况。儿科早期预警评分在急诊科也可用于快速识别危重症患者,以便立即开始治疗。本研究旨在确定一种新设计的、快速且易于使用的改良儿科早期预警评分是否可以识别急诊科的危重症患儿。本研究为荷兰鹿特丹市一家城区医院急诊科的回顾性观察性研究。纳入因内科问题就诊急诊科的<16 岁患儿。立即转入重症监护病房作为危重症患儿的衡量标准。研究期间,共有 2980 名患儿就诊急诊科,其中 10 名(0.4%)患儿需要立即转入重症监护病房。改良儿科早期预警评分可用于识别普通儿科急诊人群中的危重症患儿(ROC 曲线下面积为 0.82)。敏感度为 80%,特异度为 85%,提示当这些结果在更大的人群中得到验证时,该评分可能有助于排除急诊科就诊患儿的危重病。包含改良儿科早期预警评分和曼彻斯特分诊系统的模型与单独使用曼彻斯特分诊系统相比,其性能并无显著提高,但该模型显示出有利于包含改良儿科早期预警评分和曼彻斯特分诊系统的倾向,ROC 曲线下面积为 0.89[95%CI 0.77-1.00],而 ROC 曲线下面积为 0.82[95%CI 0.68-0.95]。结论:在这项可行性研究中,改良儿科早期预警评分可能是一种快速且易于使用的工具,可用于识别普通儿科急诊人群中的危重症患儿。如果将改良儿科早期预警评分与曼彻斯特分诊系统等分诊系统相结合,可能会提高其效能。需要进一步的前瞻性研究来证实我们的结果。已知:•儿科早期预警评分可识别急诊科需要立即转入重症监护病房的患儿。•儿科早期预警评分可能耗时较长,包含主观参数或难以以可靠和标准化的方式获得的参数。新发现:•我们基于现有的、先前研究过的儿科早期预警评分,在袖珍卡片上引入了一种简化、易于管理和巧妙设计的改良儿科早期预警评分。•在这项可行性研究中,改良儿科早期预警评分预测急诊科立即转入重症监护病房的诊断性能与原始儿科早期预警评分一致,但需要在更大范围内进行验证。