Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Department of Health Sciences, Gettysburg College, Gettysburg, PA 17325, USA.
Int J Environ Res Public Health. 2018 Nov 13;15(11):2544. doi: 10.3390/ijerph15112544.
Household air pollution is estimated to be responsible for nearly three million premature deaths annually. Measuring fractional exhaled nitric oxide (FeNO) may improve the limited understanding of the association of household air pollution and airway inflammation. We evaluated the cross-sectional association of FeNO with exposure to household air pollution (24-h average kitchen and personal fine particulate matter and black carbon; stove type) among 139 women in rural Honduras using traditional stoves or cleaner-burning stoves. We additionally evaluated interaction by age. Results were generally consistent with a null association; we did not observe a consistent pattern for interaction by age. Evidence from ambient and household air pollution regarding FeNO is inconsistent, and may be attributable to differing study populations, exposures, and FeNO measurement procedures (e.g., the flow rate used to measure FeNO).
家庭空气污染估计每年导致近 300 万人过早死亡。测量呼出气中一氧化氮分数（FeNO）可能会改善对家庭空气污染和气道炎症关联的有限理解。我们评估了 139 名居住在农村洪都拉斯的女性的 FeNO 与家庭空气污染（24 小时平均厨房和个人细颗粒物及黑碳；炉灶类型）暴露之间的横断面关联，这些女性使用传统炉灶或燃烧更清洁的炉灶。我们还评估了年龄的交互作用。结果通常与零关联一致；我们没有观察到年龄交互作用的一致模式。关于 FeNO 的环境和家庭空气污染的证据不一致，这可能归因于不同的研究人群、暴露和 FeNO 测量程序（例如，用于测量 FeNO 的流速）。
