Division of Sports Science, Pusan National University, Busan, Republic of Korea.
Division of Sports Science, Pusan National University, Busan, Republic of Korea.
Exp Gerontol. 2019 Jan;115:62-68. doi: 10.1016/j.exger.2018.11.009. Epub 2018 Nov 16.
Geriatric depression is common due to the high rate of chronic diseases suffered by the older population. There is a well-established effect of exercise on one's wellbeing, however, for the elderly females there is dearth in research addressing exercise and its effect on their neurotransmitters and depression score. Therefore, this study aimed to investigate the effects of 24 weeks of the Growing Stronger program on neurotransmitter and depression of older women.
Twenty-one older women, aged between 67 and 81, participated in this study. The participants were randomly assigned into a strength exercise (n = 11) and control group (n = 10) (age 76.40 ± 3.27, height 152.77 ± 5.63 kg, Weight 52.35 ± 2.86Kg, BMI 22.50 ± 1.88). The strength exercise group (age 76.10 ± 3.85, height 151.14 ± 5.42 kg, Weight 54.74 ± 6.73Kg, BMI 23.96 ± 2.70) participated for 50-80 min a day three times per week for a total of 24 weeks. All participants had their height, weight, blood testing and depression score tested before and after the training program. Two-way ANOVA with effect sizes was used to identify differences between times in each group and the statistical significance was set at 0.05.
In neurotransmitter factor, serotonin, dopamine, epinephrine, and norepinephrine significantly decreased in the strength exercise group but not for the control group. Notably, one participant whose serotonin level was lower than normal range before the exercise program showed normal level in serotonin after the program. In depression factor, there were no significant differences for both the strength exercise group and control group.
The results suggest that the effect of strength exercise on neurotransmitter and depression score remain unclear, but highlight the need for future studies investigating the relationship between strength training and depression.
由于老年人群患慢性病的比率较高，老年抑郁症较为常见。运动对人的幸福感有明显的影响，但是对于老年女性来说，关于运动及其对神经递质和抑郁评分的影响的研究还很缺乏。因此，本研究旨在调查 24 周“成长更强”计划对老年女性神经递质和抑郁的影响。
21 名年龄在 67 岁至 81 岁之间的老年女性参与了这项研究。参与者被随机分配到力量训练组（n=11）和对照组（n=10）（年龄 76.40±3.27，身高 152.77±5.63kg，体重 52.35±2.86kg，BMI 22.50±1.88）。力量训练组（年龄 76.10±3.85，身高 151.14±5.42kg，体重 54.74±6.73kg，BMI 23.96±2.70）每天参加 50-80 分钟的训练，每周三次，共 24 周。所有参与者在训练计划前后都进行了身高、体重、血液检测和抑郁评分测试。采用双因素方差分析和效应大小来确定每组内不同时间的差异，统计显著性设为 0.05。
在神经递质因子方面，力量训练组的血清素、多巴胺、肾上腺素和去甲肾上腺素显著下降，但对照组没有。值得注意的是，一名在运动前血清素水平低于正常范围的参与者，在运动后其血清素水平恢复正常。在抑郁因子方面，力量训练组和对照组均无显著差异。
结果表明，力量训练对神经递质和抑郁评分的影响尚不清楚，但强调了需要进一步研究力量训练与抑郁之间的关系。
