Adinew Getnet Mequanint, Woredekal Asegedech Tsegaw, DeVos Elizabeth L, Birru Eshetie Melese, Abdulwahib Mohammed Birhan
Department of pharmacology, School of Pharmacy, College of Medicine and Health Science, University of Gondar, Ethiopia.
University of Florida College of Medicine-Jacksonville, United States.
Afr J Emerg Med. 2017 Jun;7(2):74-78. doi: 10.1016/j.afjem.2017.04.005. Epub 2017 Apr 20.
With the widespread availability of a vast number of chemicals and drugs, acute poisoning is a common medical emergency worldwide. In spite of the success of interventions to prevent toxic ingestions, acute poisoning continues to be an important public health problem. Because of weak regulations and limited health care services in developing countries, adverse outcomes from poisoning are more prevalent than in the developed world. Due to the limited Ethiopian literature on this topic, the primary objective of this study was to evaluate and report poisoning cases, their management and outcome in northwest Ethiopia.
This is a retrospective study of all poisoning cases admitted and managed in the emergency centres of Gondar Teaching Referral Hospital and Metema and Debark district hospitals, from September 2010 to December 2014. Data was collected through retrospective chart review of patients who were admitted due to poisoning.
There were 543 registered poisoning cases listed in the registry during the study period, of which 344 cases (63.4%) had complete data and were included in the final analysis. There were 48,619 emergency centre visits during the study period, with poisoning cases accounting for 1.1%. Females (60%) were predominant among intentional as well as unintentional poisoning cases. Patients between 15 and 24 years of age accounted for 55% of the cases. Patients poisoned with organophosphate and bleaching agents accounted for 35% and 25%, respectively. Among the poisoning patients, 74% were treated with decontamination, while those exposed to organophosphate were treated with atropine 45.5% (55/121) of the time.
Young females comprise a group at increased risk for suicidal poisonings. As a developing nation, pesticide and bleaching agents remain a significant cause of acute poisonings in Ethiopia. Intentional poisoning remains the most significant identified cause of poisoning overall.
随着大量化学品和药物的广泛可得,急性中毒是全球常见的医疗紧急情况。尽管在预防有毒物质摄入的干预措施方面取得了成功,但急性中毒仍然是一个重要的公共卫生问题。由于发展中国家监管薄弱且医疗服务有限,中毒的不良后果比发达国家更为普遍。由于埃塞俄比亚关于该主题的文献有限,本研究的主要目的是评估并报告埃塞俄比亚西北部的中毒病例、其管理情况及结果。
这是一项对2010年9月至2014年12月期间在贡德尔教学转诊医院以及梅特马和德巴克地区医院的急诊中心收治和管理的所有中毒病例进行的回顾性研究。通过对因中毒入院患者的病历进行回顾性审查来收集数据。
在研究期间登记册上列出了543例注册中毒病例,其中344例(63.4%)有完整数据并纳入最终分析。研究期间急诊中心就诊48,619人次,中毒病例占1.1%。在故意和非故意中毒病例中女性(60%)占主导。15至24岁的患者占病例的55%。有机磷和漂白剂中毒患者分别占35%和25%。在中毒患者中,74%接受了去污治疗,而接触有机磷的患者有45.5%(55/121)的时间接受了阿托品治疗。
年轻女性是自杀性中毒风险增加的群体。作为一个发展中国家,农药和漂白剂仍然是埃塞俄比亚急性中毒的重要原因。故意中毒仍然是总体上确定的中毒的最重要原因。