Park Justin J, Chung Christopher S, Fawzi Amani A
Ophthalmic Surg Lasers Imaging Retina. 2018 Nov 1;49(11):e182-e190. doi: 10.3928/23258160-20181101-16.
To assess the relationship between retinal vascular and structural changes in the superficial, middle, and deep capillary plexuses (SCP, MCP, DCP) using optical coherence tomography angiography (OCTA) and en face OCT.
Patients with diabetic retinopathy were imaged using the Cirrus HD-OCT with AngioPlex. Using manual segmentation of the retinal layers, the authors compared OCTA to en face OCT images to examine corresponding patterns in each of the three capillary plexuses.
Areas of decreased perfusion and capillary dropout on OCTA were found to be associated with three corresponding lesions on en face OCT: hyporeflectivity, cystic edema, and hard exudates. Vascular changes in individual capillary plexuses corresponded with structural changes in their respective perfused retinal layers.
Using manual segmentation on OCTA, the authors provide a framework to visualize the relationship between vascular pathology on OCTA and structural changes on en face OCT within specific capillary plexuses. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e182-e190.].
使用光学相干断层扫描血管造影（OCTA）和表面增强光学相干断层扫描（en face OCT）评估浅表、中间和深部毛细血管丛（SCP、MCP、DCP）中视网膜血管和结构变化之间的关系。
使用配备AngioPlex的Cirrus HD-OCT对糖尿病视网膜病变患者进行成像。作者通过手动分割视网膜层，将OCTA与en face OCT图像进行比较，以检查三个毛细血管丛中各自的对应模式。
发现OCTA上灌注减少和毛细血管缺失的区域与en face OCT上的三种相应病变相关：低反射性、囊性水肿和硬性渗出。各个毛细血管丛中的血管变化与其各自灌注的视网膜层中的结构变化相对应。
作者通过对OCTA进行手动分割，提供了一个框架，以可视化特定毛细血管丛中OCTA上的血管病变与en face OCT上的结构变化之间的关系。[《眼科手术、激光与视网膜成像》。2018年；49：e182 - e190。]
