White C J, Kwon-Chung K J, Gallin J I
Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
Am J Clin Pathol. 1988 Sep;90(3):312-6. doi: 10.1093/ajcp/90.3.312.
Aspergillus nidulans var. echinulatus was the sole agent cultured from the left lung, a paraspinal abscess, left ribs, and thoracic vertebral bodies from a patient with chronic granulomatous disease. Hyphal elements were present in histologic sections of lung, vertebral bodies, and infected ribs along with granuloma formation. The patient was treated with two debridement procedures and insertion of a Harrington rod followed by a long course of amphotericin B, flucytosine, and daily white blood cell transfusions.
棘孢构巢曲霉是从一名慢性肉芽肿病患者的左肺、椎旁脓肿、左侧肋骨和胸椎椎体中培养出的唯一病原体。在肺、椎体和受感染肋骨的组织切片中发现了菌丝成分，并伴有肉芽肿形成。该患者接受了两次清创手术并植入了哈灵顿棒，随后长期使用两性霉素B、氟胞嘧啶治疗，并每日输注白细胞。
