抗疟药：氯喹耐药机制 - Suppr

Suppr

超能文献

Antimalarial agents: mechanism of chloroquine resistance.

作者信息

Krogstad D J, Schlesinger P H, Herwaldt B L

机构信息

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

出版信息

Antimicrob Agents Chemother. 1988 Jun;32(6):799-801. doi: 10.1128/AAC.32.6.799.

DOI:10.1128/AAC.32.6.799

PMID:3046480

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172285/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/999d/172285/ef2b00cb0a4d/aac00085-0027-a.jpg

相似文献

Antimalarial agents: mechanism of chloroquine resistance.抗疟药：氯喹耐药机制

Antimicrob Agents Chemother. 1988 Jun;32(6):799-801. doi: 10.1128/AAC.32.6.799.

Selective antimalarial activity of tetrandrine against chloroquine resistant Plasmodium falciparum.粉防己碱对氯喹耐药恶性疟原虫的选择性抗疟活性。

Biochem Biophys Res Commun. 1989 Feb 28;159(1):242-8. doi: 10.1016/0006-291x(89)92429-7.

3-Halo Chloroquine Derivatives Overcome Plasmodium falciparum Chloroquine Resistance Transporter-Mediated Drug Resistance in P. falciparum.3-卤代氯喹衍生物克服恶性疟原虫中氯喹抗性转运蛋白介导的恶性疟原虫耐药性。

Antimicrob Agents Chemother. 2015 Dec;59(12):7891-3. doi: 10.1128/AAC.01139-15. Epub 2015 Oct 5.

Chloroquine resistance in the malarial parasite, Plasmodium falciparum.恶性疟原虫对氯喹的耐药性。

Med Res Rev. 2002 Sep;22(5):465-91. doi: 10.1002/med.10016.

In vitro antimalarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates.长叶刺蒺藜提取物中苦木素类化合物对马来西亚氯喹耐药恶性疟原虫分离株的体外抗疟活性。

Planta Med. 1995 Apr;61(2):177-8. doi: 10.1055/s-2006-958042.

Synthesis and in vitro evaluation of new chloroquine-chalcone hybrids against chloroquine-resistant strain of Plasmodium falciparum.合成及体外评价新型氯喹-查尔酮杂合体对恶性疟原虫氯喹抗性株的作用。

Bioorg Med Chem Lett. 2012 Sep 1;22(17):5455-9. doi: 10.1016/j.bmcl.2012.07.028. Epub 2012 Jul 14.

A longitudinal study of P. falciparum response to chloroquine in relation to the epidemiology.

J Commun Dis. 1989 Sep;21(3):229-40.

Drug resistance in malaria: a review of the west African situation.疟疾中的耐药性：西非情况综述

J Natl Med Assoc. 1992 Dec;84(12):1025-9.

[Research progress on chloroquine resistance in Plasmodium falciparum and resistance reversal agent].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2008 Apr;26(2):141-5.

Plasmodium falciparum chloroquine resistance marker protein (Pfcrmp) may be a chloroquine target protein in nucleus.恶性疟原虫氯喹抗性标记蛋白（Pfcrmp）可能是细胞核中的一种氯喹靶蛋白。

Med Hypotheses. 2007;68(2):332-4. doi: 10.1016/j.mehy.2006.07.016. Epub 2006 Sep 25.

引用本文的文献

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria.全细胞通路筛选发现七种新型化学增敏剂，以对抗氯喹耐药疟疾。

Sci Rep. 2013;3:1734. doi: 10.1038/srep01734.

The mechanism of antimalarial action of [Au(CQ)(PPh(3))]PF(6): structural effects and increased drug lipophilicity enhance heme aggregation inhibition at lipid/water interfaces.[Au(CQ)(PPh(3))]PF(6)抗疟作用机制：结构效应和增加药物脂溶性增强了在油水界面处对血红素聚集的抑制作用。

J Inorg Biochem. 2011 Feb;105(2):276-82. doi: 10.1016/j.jinorgbio.2010.11.005. Epub 2010 Nov 13.

In vivo screening of antimalarial activity of Acacia mellifera (Benth) (Leguminosae) on Plasmodium berghei in mice.阿拉伯胶树（金合欢属，豆科）对小鼠体内伯氏疟原虫抗疟活性的体内筛选。

Afr J Tradit Complement Altern Med. 2007 Oct 27;5(1):46-50.

Carrier-mediated partitioning of artemisinin into Plasmodium falciparum-infected erythrocytes.载体介导的青蒿素在恶性疟原虫感染红细胞中的分配。

Antimicrob Agents Chemother. 2002 Jan;46(1):105-9. doi: 10.1128/AAC.46.1.105-109.2002.

Antimalarial agents: specific treatment regimens.抗疟药：特定治疗方案

Antimicrob Agents Chemother. 1988 Jul;32(7):957-61. doi: 10.1128/AAC.32.7.957.

Antimalarial agents: specific chemoprophylaxis regimens.抗疟药：特定的化学预防方案。

Antimicrob Agents Chemother. 1988 Jul;32(7):953-6. doi: 10.1128/AAC.32.7.953.

Antimalarial agents: mechanisms of action.抗疟药：作用机制

Antimicrob Agents Chemother. 1988 Jun;32(6):793-8. doi: 10.1128/AAC.32.6.793.

Treatment of malaria--1990.疟疾的治疗——1990年。

Drugs. 1990 Feb;39(2):160-89. doi: 10.2165/00003495-199039020-00002.

本文引用的文献

Plasmodium falciparum in owl monkeys: drug resistance and chloroquine binding capacity.猫头鹰猴体内的恶性疟原虫：耐药性与氯喹结合能力

Science. 1970 Jul 17;169(3942):289-90. doi: 10.1126/science.169.3942.289.

Chloroquine-resistant Plasmodium falciparum: difference in the handling of 14C-amodiaquin and 14C-chloroquine.耐氯喹恶性疟原虫：14C-阿莫地喹和14C-氯喹处理的差异

Antimicrob Agents Chemother. 1973 May;3(5):545-8. doi: 10.1128/AAC.3.5.545.

Reduced drug accumulation in multiply drug-resistant human KB carcinoma cell lines.多重耐药性人KB癌细胞系中药物蓄积减少。

Cancer Res. 1985 Jul;45(7):3002-7.

Antimalarials increase vesicle pH in Plasmodium falciparum.抗疟药会提高恶性疟原虫中的囊泡pH值。

J Cell Biol. 1985 Dec;101(6):2302-9. doi: 10.1083/jcb.101.6.2302.

P-glycoprotein expression in human breast cancer cells.人乳腺癌细胞中的P-糖蛋白表达

Cancer Res. 1987 Apr 15;47(8):2103-6.

Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells.长春碱与多药耐药KB细胞膜囊泡的结合增加。

J Biol Chem. 1986 Jun 15;261(17):7921-8.

Inoculum effect with chloroquine and Plasmodium falciparum.氯喹与恶性疟原虫的接种效应。

Antimicrob Agents Chemother. 1987 Jan;31(1):32-6. doi: 10.1128/AAC.31.1.32.

Reversal of chloroquine resistance in Plasmodium falciparum by verapamil.维拉帕米逆转恶性疟原虫对氯喹的耐药性。

Science. 1987 Feb 20;235(4791):899-901. doi: 10.1126/science.3544220.

Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum.药物敏感和耐药的人类疟原虫恶性疟原虫菌株对[3H]氯喹的摄取情况。

Biochem Pharmacol. 1986 Nov 1;35(21):3805-12. doi: 10.1016/0006-2952(86)90668-4.

The basis of multidrug resistance in mammalian cells: homology with bacterial transport.

Cell. 1986 Nov 7;47(3):323-4. doi: 10.1016/0092-8674(86)90585-4.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验