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经痛宁对原发性痛经的影响:一项随机临床试验。

Effect of Menstrugole on primary dysmenorrhea: a randomized clinical trial.

作者信息

Shobeiri Fatemeh, Nazari Sasan, Nazari Saman, Jenabi Ensiyeh, Shayan Arezoo

机构信息

Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.

Students Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Obstet Gynecol Sci. 2018 Nov;61(6):684-687. doi: 10.5468/ogs.2018.61.6.684. Epub 2018 Oct 11.

DOI:10.5468/ogs.2018.61.6.684
PMID:30474015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6236095/
Abstract

OBJECTIVE

Primary dysmenorrhea occurs in more than 50% of women of reproductive age. This survey evaluated the effects of Menstrugole on the alleviation of primary dysmenorrhea.

METHODS

This study was performed in western Iran between August 15 and December 15, 2017, in female students with primary dysmenorrhea. The students were randomly divided into 2 groups and received placebo or a Menstrugole capsule for 3 days in each of 2 menstrual cycles. The visual analog scale was used to assess pain severity. The χ test, one-way analysis of variance, and the paired -test were used for statistical evaluation.

RESULTS

We compared the severity of pain between the 2 groups. There was a significant change in the mean pain score during the first (<0.001) and second months (<0.001) after the use of Menstrugole, compared with that in the placebo group.

CONCLUSION

Menstrugole decreased pain severity in female students, and can be considered by health care providers for treatment of primary dysmenorrhea.

摘要

目的

超过50%的育龄女性会出现原发性痛经。本调查评估了Menstrugole对缓解原发性痛经的效果。

方法

本研究于2017年8月15日至12月15日在伊朗西部对患有原发性痛经的女学生进行。学生们被随机分为两组,在两个月经周期中的每个周期服用3天安慰剂或Menstrugole胶囊。采用视觉模拟评分法评估疼痛严重程度。使用χ检验、单因素方差分析和配对检验进行统计学评估。

结果

我们比较了两组之间的疼痛严重程度。与安慰剂组相比,使用Menstrugole后的第一个月(<0.001)和第二个月(<0.001)平均疼痛评分有显著变化。

结论

Menstrugole降低了女学生的疼痛严重程度,医疗保健人员可考虑将其用于原发性痛经的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8864/6236095/842616b6c5e6/ogs-61-684-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8864/6236095/842616b6c5e6/ogs-61-684-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8864/6236095/842616b6c5e6/ogs-61-684-g001.jpg

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Efficacy of Ginger for Alleviating the Symptoms of Primary Dysmenorrhea: A Systematic Review and Meta-analysis of Randomized Clinical Trials.生姜缓解原发性痛经症状的疗效:随机临床试验的系统评价和荟萃分析
Pain Med. 2015 Dec;16(12):2243-55. doi: 10.1111/pme.12853. Epub 2015 Jul 14.
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草药对原发性痛经的影响——一项系统评价
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Sildenafil citrate in the treatment of pain in primary dysmenorrhea: a randomized controlled trial.枸橼酸西地那非治疗原发性痛经疼痛:一项随机对照试验。
Hum Reprod. 2013 Nov;28(11):2958-65. doi: 10.1093/humrep/det324. Epub 2013 Aug 6.
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The effect of ginger for relieving of primary dysmenorrhoea.生姜缓解原发性痛经的效果。
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