Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 56212, Republic of Korea.
Chem Commun (Camb). 2019 Jan 3;55(4):447-450. doi: 10.1039/c8cc08304e.
As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.
作为一种强大的放射分析方法，用于追踪体内的碳质颗粒，柴油废气中的多环芳烃被放射性碘标记的苝类似物标记。单光子发射计算机断层扫描和生物分布研究表明，这种物质在呼吸系统中的摄取量很高，清除速度很慢，这可能是其严重毒性的基础。
