Department of Medicine, Division of Medical Ethics, Donald and Barbara Zucker School of Medicine at Hofstra University/Northwell Health, New York, New York 11040.
Cold Spring Harb Perspect Med. 2019 Oct 1;9(10):a034363. doi: 10.1101/cshperspect.a034363.
Bioelectronic medicine (BEM) offers exciting opportunities to treat diseases such as movement disorders and refractory inflammatory disease. The many variations of BEM allow for noninvasive aspects of treatment that might eliminate or reduce the need for pharmaceuticals; therefore, the term "electroceuticals" may be suitable. BEM has been effective for movement disorders and improvement of prosthetic devices. Based on this implication, there is an allowance to impact many focus areas that include but are not limited to autoimmune disease, sensory motor conditions, and neurological conditions. There are a wide array of ethical issues that relate to BEM, which include informed consent, research ethics, innovation, academic-industry relationships, intellectual property, and the conundrum that needs to be addressed when altering the brain such as the issues of autonomy and free beneficence and social justice. The major goal is to heighten awareness of ethical issues and facilitate a proactive ethical approach regarding BEM research.
生物电子医学（BEM）为治疗运动障碍和难治性炎症性疾病等疾病提供了令人兴奋的机会。BEM 的多种变化允许治疗具有非侵入性的方面，这可能消除或减少对药物的需求；因此，“电子药物”这个术语可能是合适的。BEM 对运动障碍和改善假肢设备非常有效。基于这一含义，可以允许影响许多重点领域，包括但不限于自身免疫性疾病、感觉运动疾病和神经疾病。BEM 涉及广泛的伦理问题，包括知情同意、研究伦理、创新、学术-工业关系、知识产权，以及在改变大脑时需要解决的难题，如自主性和自由行善以及社会正义的问题。主要目标是提高对 BEM 研究中伦理问题的认识，并促进积极的伦理方法。
