Cohen J C, Schall R
Sport Science Centre, University of Cape Town, South Africa.
Am J Clin Nutr. 1988 Oct;48(4):1031-4. doi: 10.1093/ajcn/48.4.1031.
The effects of glucose, sucrose, and fructose ingestion on the serum triglyceride responses to meals containing 40 g fat were studied in 21 normolipidemic, nonobese medical students (9 men, 12 women). Mean postprandial lipemia was not significantly lower after meals containing 50 g glucose and 40 g fat than after meals containing 40 g fat alone (2.11 vs 2.42 mmol.L-1.7 h-1, p greater than 0.45) despite a substantial increase in plasma insulin concentrations after the glucose-containing meal. Ingestion of 50 g fructose and 40 g fat (4.23 mmol.L-1.7 h-1, p less than 0.0001) and 100 g sucrose and 40 g fat (3.77 mmol.L-1.7 h-1, p less than 0.001) resulted in significantly greater lipemia than did the ingestion of fat alone. These findings suggest that the ingestion of insulinogenic carbohydrates does not reduce postprandial lipemia in normolipidemic subjects and that the ingestion of fructose and fructose-containing carbohydrates may augment the postprandial lipemia induced by a fat-containing meal.
在21名血脂正常、不肥胖的医科学生（9名男性，12名女性）中，研究了摄入葡萄糖、蔗糖和果糖对含40克脂肪餐食后血清甘油三酯反应的影响。尽管含葡萄糖餐食后血浆胰岛素浓度大幅升高，但含50克葡萄糖和40克脂肪的餐食后餐后血脂水平并不显著低于仅含40克脂肪的餐食（分别为2.11和2.42毫摩尔·升⁻¹·7小时⁻¹，p＞0.45）。摄入50克果糖和40克脂肪（4.23毫摩尔·升⁻¹·7小时⁻¹，p＜0.0001）以及100克蔗糖和40克脂肪（3.77毫摩尔·升⁻¹·7小时⁻¹，p＜0.001）导致的血脂水平显著高于仅摄入脂肪。这些发现表明，摄入促胰岛素生成的碳水化合物不会降低血脂正常受试者的餐后血脂水平，并且摄入果糖和含果糖的碳水化合物可能会增强含脂肪餐食引起的餐后血脂水平。
