Cohen J C, Noakes T D, Benade A J
Department of Physiology, University of Cape Town Medical School, Republic of South Africa.
Am J Clin Nutr. 1988 May;47(5):825-7. doi: 10.1093/ajcn/47.5.825.
To determine the dose response of serum triglyceride concentrations to fat feeding, serum triglyceride responses to meals containing 40, 80, and 120 g fat (in the form of dairy cream) were measured in 12 normotriglyceridemic men. Mean postprandial lipemia (measured as the integrated area under the curve of serum triglyceride concentration plotted against time) was 251 +/- 129 mg.dL-1.8 h-1 (2.83 +/- 1.46 mmol.L-1.8 h-1) after the 40-g-fat meal, 503 +/- 233 mg.dL-18 h-1 (5.68 +/- 2.63 mmol.L-1.8 h-1) after the 80-g-fat meal, and 712 +/- 281 mg.dL-1.8 h-1 (8.04 +/- 3.17 mmol.L-1.8 h-1) after the 120-g-fat meal. These data indicate that in normotriglyceridemic men the magnitude of lipemia that follows the ingestion of a fat meal is directly proportional to the fat content of the meal. The results also suggest that the mechanism whereby triglyceride is removed from the intravascular compartment is not saturated by meals containing the amounts of fat typically consumed by men following a Western diet.
为确定血清甘油三酯浓度对脂肪摄入的剂量反应，对12名正常甘油三酯血症男性测定了其对含40克、80克和120克脂肪（以乳脂形式）餐食的血清甘油三酯反应。40克脂肪餐食后，餐后平均血脂（以血清甘油三酯浓度随时间绘制曲线下的积分面积衡量）为251±129毫克·分升⁻¹·8小时⁻¹（2.83±1.46毫摩尔·升⁻¹·8小时⁻¹）；80克脂肪餐食后为503±233毫克·分升⁻¹·8小时⁻¹（5.68±2.63毫摩尔·升⁻¹·8小时⁻¹）；120克脂肪餐食后为712±281毫克·分升⁻¹·8小时⁻¹（8.04±3.17毫摩尔·升⁻¹·8小时⁻¹）。这些数据表明，在正常甘油三酯血症男性中，摄入脂肪餐后出现的血脂水平与餐食中的脂肪含量直接成正比。结果还表明，从血管内清除甘油三酯的机制不会因含有西方饮食模式下男性通常摄入量的脂肪餐食而饱和。
