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仿生碳量子点:一种抗生物膜剂。

Bioinspired Carbon Quantum Dots: An Antibiofilm Agents.

机构信息

Centre for Materials for Electronics Technology (C-MET), Ministry of Electronics and Information Technology (MeitY), Government of India, Panchawati Off Pashan Road, Pune 411008, India.

Department of Biotechnology, Savitribai Phule Pune University, Pune 411007, India.

出版信息

J Nanosci Nanotechnol. 2019 Apr 1;19(4):2339-2345. doi: 10.1166/jnn.2019.16537.

DOI:10.1166/jnn.2019.16537
PMID:30486995
Abstract

Carbon dots, very tiny carbon material with various surface passivations, have emerged as a new class of nanomaterials for various applications. Herein, we describe a simple, economical, and green approach for the synthesis of colloidal luminescent carbon dots (C-dots) by solvothermal method from fruit juice of , an abundantly available plant in Asian countries. The existence of C-dots was confirmed by X-ray Diffraction and High Resolution Transmission Electron Microscopy studies. The C-dots size was observed to be 2-4 nm. We further evaluated the efficacy of C-dots to inhibit the attachment of MTCC 227, and biofilm formation on the polystyrene surfaces. The C-dots have effectively inhibited the attachment and formation of biofilm in at very low concentrations, which is hitherto unattempted. The ability of C-dots to inhibit biofilm formation may contribute to diverse applications of C-dots in biomedical field.

摘要

碳点是一种具有各种表面钝化的微小碳材料,已成为各种应用的新型纳米材料。在此,我们描述了一种简单、经济、环保的方法,通过溶剂热法从亚洲国家大量存在的植物 的果汁中合成胶体发光碳点 (C-dots)。X 射线衍射和高分辨率透射电子显微镜研究证实了 C-dots 的存在。观察到 C-dots 的尺寸为 2-4nm。我们进一步评估了 C-dots 抑制 MTCC 227 附着和在聚苯乙烯表面形成生物膜的功效。在非常低的浓度下,C-dots 有效地抑制了附着和生物膜的形成,这是迄今为止尚未尝试过的。C-dots 抑制生物膜形成的能力可能有助于 C-dots 在生物医学领域的多种应用。

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