Tudosescu Ruxandra, Alexandrescu Cristina Mihaela, Istrate Sinziana Luminita, Vrapciu Alexandra, Ciuluvica Radu Constantin, Voinea Liliana Mary
Ophthalmology Department, Regina Maria Private Health Care Network, Dorobanti Hyperclinic, Bucharest, Romania.
Ophthalmology Department, Bucharest University Emergency Hospital, Bucharest, Romania.
Rom J Ophthalmol. 2018 Jul-Sep;62(3):222-227.
To present a series of 2 cases of central serous chorioretinopathy and the changes in the macular pigment optical density during the evolution of the disease. A 32-year-old patient presented himself for blurred vision on his LE. The SD OCT imaging revealed serous macular detachment of the neurosensory retina on the LE. The MPOD results were 0.72 on RE and 0.91 on LE. After treatment and resorption of the subretinal fluid, the MPOD values were 0.72 on the RE and 0.82 on the LE. The second patient was a 36-year-old male with metamorphopsia on LE and serous macular detachment on this eye. The MPOD results were 0.43 on RE and 0.58 on the LE and, after treatment, they were 0.38 on the RE and 0.43 on the LE. Central serous chorioretinopathy is a disease of unknown pathophysiology in which we observed a higher MPOD on the eye with CSC than on the fellow eye and a decrease in the MPOD value after the resorption of the subretinal fluid. L = lutein, Z = zeaxantin, MZ = mezozeaxantin, AMD = age related macular degeneration, MPOD = macular pigment optical density, MP = macular pigment, HFP = Heterochromatic Flicker Photometry, CSC = central serous chorioretinopathy, RE = right eye, LE = left eye.
报告2例中心性浆液性脉络膜视网膜病变病例以及疾病演变过程中黄斑色素光密度的变化。一名32岁患者因左眼视力模糊前来就诊。SD OCT成像显示左眼神经感觉视网膜浆液性黄斑脱离。右眼的黄斑色素光密度(MPOD)结果为0.72,左眼为0.91。在视网膜下液吸收及治疗后,右眼的MPOD值为0.72,左眼为0.82。第二名患者是一名36岁男性,左眼有视物变形,该眼存在浆液性黄斑脱离。右眼的MPOD结果为0.43,左眼为0.58,治疗后,右眼为0.38,左眼为0.43。中心性浆液性脉络膜视网膜病变是一种病理生理学不明的疾病,我们观察到患有中心性浆液性脉络膜视网膜病变(CSC)的眼睛的MPOD高于对侧眼,且视网膜下液吸收后MPOD值降低。L = 叶黄素,Z = 玉米黄质,MZ = 内消旋玉米黄质,AMD = 年龄相关性黄斑变性,MPOD = 黄斑色素光密度,MP = 黄斑色素,HFP = 异色闪烁光度法,CSC = 中心性浆液性脉络膜视网膜病变,RE = 右眼,LE = 左眼。