John Wiley & Sons, Inc., Hoboken, New Jersey.
Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York.
Brain Behav. 2019 Jan;9(1):e01141. doi: 10.1002/brb3.1141. Epub 2018 Dec 2.
Progress in basic and clinical research is slowed when researchers fail to provide a complete and accurate report of how a study was designed, executed, and the results analyzed. Publishing rigorous scientific research involves a full description of the methods, materials, procedures, and outcomes. Investigators may fail to provide a complete description of how their study was designed and executed because they may not know how to accurately report the information or the mechanisms are not in place to facilitate transparent reporting. Here, we provide an overview of how authors can write manuscripts in a transparent and thorough manner. We introduce a set of reporting criteria that can be used for publishing, including recommendations on reporting the experimental design and statistical approaches. We also discuss how to accurately visualize the results and provide recommendations for peer reviewers to enhance rigor and transparency. Incorporating transparency practices into research manuscripts will significantly improve the reproducibility of the results by independent laboratories.
当研究人员未能完整准确地报告研究的设计、执行和结果分析时,基础和临床研究的进展就会放缓。发表严谨的科学研究需要全面描述方法、材料、程序和结果。研究人员可能无法完整描述他们的研究设计和执行情况,因为他们可能不知道如何准确报告信息,或者没有机制来促进透明报告。在这里,我们提供了一个概述,说明作者如何以透明和彻底的方式撰写手稿。我们引入了一套可用于出版的报告标准,包括有关报告实验设计和统计方法的建议。我们还讨论了如何准确地可视化结果,并为同行评审员提供建议,以提高严谨性和透明度。将透明实践纳入研究手稿将显著提高独立实验室对结果的可重复性。