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Impact of uncertainties related to noise indicator determination on observed exposure-effect relationship.

作者信息

Kirisits Christian, Lechner Christoph, Kirisits Helmut

机构信息

Kirisits Consulting Engineers, Pinkafeld/Vienna; Department of Radiotherapy, Medical University of Vienna, Vienna, Austria.

Department of Public Health, Health Services Research and Health Technology Assessment, UMIT-University for Health Sciences, Medical Informatics and Technology, Hall in Tirol, Austria.

出版信息

Noise Health. 2018 Sep-Oct;20(96):212-216. doi: 10.4103/nah.NAH_57_17.

DOI:10.4103/nah.NAH_57_17
PMID:30516174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6301088/
Abstract

CONTEXT

Noise indicators are the basis to describe noise exposure-effect relationships. The assessment of these noise indicators in field studies includes various uncertainties, so that the true values differ from the determined values used for establishing curve fits. If the relationship between a noise indicator and its effect is nonlinear, uncertainties of the noise indicator modify the observed exposure-effect relationships.

MATERIALS AND METHODS

The determination of an exposure-relationship curve fit within a field study was simulated based on the assumption of a given true exposure-relationship without uncertainties and normal distributed uncertainties for the observed noise indicator used for the statistics.

RESULTS

In case of an upward curvature of the exposure-effect relationship, the uncertainty for the noise indicator value leads to an asymmetric effect for the curve fit. Uncertainties of the same amount of over- or underestimation will not result in an identical over- or underestimation of the observed effect. A simulation of this effect shows an increased curvature of the observed curve fit, with overestimated exposure-effect relationships.

CONCLUSION

Although linear exposure-effect curves are not observed with a systematic shift, quadratic, cubic, and exponential curve forms include a systematic uncertainty in the presented exposure-response curve. If such curves are used to define threshold levels to limit harmful effects of noise, no further uncertainty margins are needed for those situations where the calculated noise indicator uncertainties are equal or lower than those present in the underlying field study.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/c5aedf738b1f/NH-20-212-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/847a88a7c217/NH-20-212-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/64f063cdc2e5/NH-20-212-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/73bef49e3ac4/NH-20-212-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/e4e74ea7d3fe/NH-20-212-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/c5aedf738b1f/NH-20-212-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/847a88a7c217/NH-20-212-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/64f063cdc2e5/NH-20-212-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/73bef49e3ac4/NH-20-212-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/e4e74ea7d3fe/NH-20-212-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ffa/6301088/c5aedf738b1f/NH-20-212-g005.jpg

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