嗅觉棒气味辨别记忆测试：一种快速、易用、可重复使用的嗅觉记忆测试方法。

The Sniffin' Sticks Odor Discrimination Memory Test: A Rapid, Easy-to-Use, Reusable Procedure for Testing Olfactory Memory.

作者信息

Besser Gerold, Jobs Leandra, Liu David Tianxiang, Mueller Christian A, Renner Bertold

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Medical University of Vienna, Vienna, Austria.

Institute of Experimental and Clinical Pharmacology and Toxicology, Erlangen, Erlangen, Germany.

出版信息

Ann Otol Rhinol Laryngol. 2019 Mar;128(3):227-232. doi: 10.1177/0003489418818189. Epub 2018 Dec 7.

DOI:10.1177/0003489418818189

PMID:30522337

Abstract

OBJECTIVES

Neurodegenerative diseases can alter odor memory in addition to inducing quantitative impairment, and olfactory memory can be tested using the validated olfactory memory test with encapsulated odors (Odor Discrimination Memory Test [ODMT]). The aim of this study was to investigate the new Sniffin' Sticks ODMT (SSODMT), which is comparable with the ODMT.

METHODS

The SSODMT was administered to 48 subjects (30 women, 18 men; mean age, 34.6 ± 16.3 years). Olfactory function was assessed using the 16-item Sniffin' Sticks Identification Test. The ODMT was administered to a subgroup of 10 subjects to assess the comparability of the SSODMT and the ODMT. Test-retest reliability was studied in another 20 subjects (10 women, 10 men; mean age, 32.9 ± 16.4 years).

RESULTS

The mean SSODMT score was 10.7 ± 1.8 (range, 5-12). SSODMT test scores were significantly correlated with Sniffin' Sticks Identification Test scores ( = 0.66, < .001) and were significantly negatively correlated with subject age ( = -0.70, < .001). SSODMT and ODMT scores were highly and significantly correlated, indicating that the test results were comparable ( = 0.75, < .05). Test-retest analysis revealed a significant correlation ( = 0.68, < .001).

CONCLUSIONS

These results demonstrate the usefulness of the new SSODMT and its comparability with the ODMT. The SSODMT is an easy, rapid, and low-cost tool that is suitable for routine use in evaluating odor memory.

摘要

目的

神经退行性疾病除了会导致嗅觉功能定量受损外，还会改变气味记忆，并且可以使用经过验证的封装气味嗅觉记忆测试（气味辨别记忆测试[ODMT]）来测试嗅觉记忆。本研究的目的是调查与ODMT相当的新型嗅觉棒ODMT（SSODMT）。

方法

对48名受试者（30名女性，18名男性；平均年龄34.6±16.3岁）进行SSODMT测试。使用16项嗅觉棒识别测试评估嗅觉功能。对10名受试者的一个亚组进行ODMT测试，以评估SSODMT与ODMT的可比性。在另外20名受试者（10名女性，10名男性；平均年龄32.9±16.4岁）中研究重测信度。

结果

SSODMT的平均得分为10.7±1.8（范围为5 - 12）。SSODMT测试得分与嗅觉棒识别测试得分显著相关（r = 0.66，P <.001），并且与受试者年龄显著负相关（r = -0.70，P <.001）。SSODMT和ODMT得分高度显著相关，表明测试结果具有可比性（r = 0.75，P <.05）。重测分析显示存在显著相关性（r = 0.68，P <.001）。