Division of Applied Biomedical Science and Biotechnology, School of Health Sciences, International Medical University, No. 126, Jalan Jalil Perkasa 19, Bukit Jalil, 57000, Kuala Lumpur, Malaysia.
Plant Foods Hum Nutr. 2019 Mar;74(1):18-27. doi: 10.1007/s11130-018-0704-z.
Cancer is a preventable and treatable disease, however, the incidence rates are on the rise. Classical treatment modalities for cancer include surgery, radiotherapy and chemotherapy. However, these are associated with detrimental side effects such as nausea and emesis. Therefore, researchers currently vest interest in complementary and alternative medicines for cancer treatment and prevention. Plants such as Syzygium sp. are a common basis of complementary medicines due to its abundance of bioactive phytochemicals. Numerous natural compounds derived from Syzygium sp., such as phenolics, oleanolic acids, and betulinic acids, and dimethyl cardamonins, were reported to have anticancer effects. Many possess the ability to inhibit cell proliferation and induce apoptosis. In this review, we discuss the vast potential Syzygium sp. harbours as a source of anticancer natural compounds due to its abundance, easy acceptability, affordability and safety for regular consumption.
癌症是一种可预防和可治疗的疾病，然而，其发病率却在上升。癌症的经典治疗方法包括手术、放疗和化疗。然而，这些方法会带来恶心和呕吐等有害副作用。因此，研究人员目前对癌症治疗和预防的补充和替代药物感兴趣。植物如 Syzygium sp. 由于其丰富的生物活性植物化学物质，是补充药物的常见基础。从 Syzygium sp. 中提取的许多天然化合物，如酚类、齐墩果酸和白桦脂酸，以及二甲氧基卡丹宁，都具有抗癌作用。许多化合物具有抑制细胞增殖和诱导细胞凋亡的能力。在这篇综述中，我们讨论了 Syzygium sp. 作为抗癌天然化合物来源的巨大潜力，因为它丰富、易于接受、负担得起，并且可以安全地常规使用。
