Tumor Center, CFS, Fibromyalgia and Oxygen Ozone Therapy Unit, Mede Clinic, Sacile (PN), Italy.
Eur Rev Med Pharmacol Sci. 2018 Nov;22(22):8030-8033. doi: 10.26355/eurrev_201811_16432.
Fatigue may be cause by all cancer treatments, maybe because the tissue damage or the build-up of dead cells derived products.
At the Mede Clinic in Sacile, Pordenone, Italy, from February 2016 to May 2018 we studied 50 patients with cancer and fatigue (15 with breast cancer, 12 with lung cancer, 11 with colon cancer, 5 with renal cancer, 3 with prostate cancer, 2 with melanoma and 2 hepatocellular carcinoma). Patients were treated with Auto Hemotransfusion (GAE) according to the SIOOT (Scientific Society of Oxygen Ozone Therapy) protocols, two times a week for one month and then twice monthly as maintenance therapy.
Nineteen of them were undergoing neoplastic treatment, 10 had already ended the cancer therapy and 21 were in a palliative setting. The Fatigue Severity Scale was used to assess the extent of fatigue in patients, in order to estimate the severity of the symptom with a score from 1 to 7. No side effects were found, and 35 patients (70%) achieved a significant improvement (> 50%) of the symptoms.
Our preliminary data demonstrate that ozone therapy is a valid supportive therapy for fatigue in cancer patients, both during cancer therapy and in a palliative setting with no significant side effects.
疲劳可能是由所有癌症治疗引起的，可能是因为组织损伤或死亡细胞产物的积累。
在意大利波代诺内萨莱的 Mede 诊所，我们从 2016 年 2 月到 2018 年 5 月研究了 50 名癌症和疲劳患者（15 名乳腺癌患者，12 名肺癌患者，11 名结肠癌患者，5 名肾癌患者，3 名前列腺癌患者，2 名黑色素瘤患者和 2 名肝细胞癌患者）。患者按照 SIOOT（氧气臭氧治疗科学学会）方案接受自动输血（GAE）治疗，每周两次，持续一个月，然后每月两次作为维持治疗。
其中 19 人正在接受肿瘤治疗，10 人已经结束癌症治疗，21 人处于姑息治疗中。疲劳严重程度量表用于评估患者疲劳的程度，以便通过 1 到 7 的分数来估计症状的严重程度。未发现任何副作用，35 名患者（70%）的症状显著改善（>50%）。
我们的初步数据表明，臭氧疗法是癌症患者疲劳的一种有效的辅助治疗方法，无论是在癌症治疗期间还是在姑息治疗中，都没有明显的副作用。
