Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.
Sunnybrook Research Institute, Toronto, Canada.
Ann Biomed Eng. 2019 Mar;47(3):659-675. doi: 10.1007/s10439-018-02186-w. Epub 2018 Dec 12.
The skin provides a protective barrier to the body against the environment. Ineffective healing of damaged skin can cause a chronic wound which would increase the risk of infection and associated complications. The use of wound dressings to protect the wound and provide an optimal environment for wound repair is a common practice in the burn clinic. While traditional wound healing dressings have substantially changed the wound outcome, wound healing complications are still a challenge to healthcare. Advancements in tissue engineering, biomaterial sciences, and stem cell biology led to the development of novel dressings that not only dress the wounds but also actively contribute to the process of healing. This review discusses the various properties of the emerging wound dressings that are designed in attempts to improve wound care upon skin injury.
皮肤为人体提供了一道抵御环境侵害的屏障。受损皮肤若无法有效愈合,可能会导致慢性伤口,从而增加感染和相关并发症的风险。在烧伤科,使用伤口敷料来保护伤口并为伤口修复提供最佳环境是一种常见做法。虽然传统的伤口愈合敷料极大地改善了伤口的愈后效果,但伤口愈合并发症仍然是医疗保健领域面临的一个挑战。组织工程、生物材料科学和干细胞生物学的进步促使新型敷料的发展,这些敷料不仅可以包扎伤口,还可以积极促进愈合过程。本文综述了新兴伤口敷料的各种特性,这些敷料的设计旨在改善皮肤损伤后的伤口护理。
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